BIROn - Birkbeck Institutional Research Online

Measurement of amyloid fibril length distributions by inclusion of rotational motion in solution NMR diffusion measurements

Baldwin, A.J. and Anthony-Cahill, S.J. and Knowles, T.P.J. and Lippens, G. and Christodoulou, John and Barker, P.D. and Dobson, C.M. (2008) Measurement of amyloid fibril length distributions by inclusion of rotational motion in solution NMR diffusion measurements. Angewandte Chemie - International Edition 47 (18), pp. 3385-3387. ISSN 1433-7851.

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1002/anie.200703915

Abstract

Telling fibrils: Diffusion data obtained by solution NMR spectroscopy from flexible regions of amyloid fibrils for both rotational and translation diffusion combined is of similar magnitude to that measured using AFM and TEM (see picture). Fibrils in solution are calculated to be somewhat longer on average than those deposited on surfaces for microscopy experiments, which can be partially attributed to the sensitivity of fibrils to fracture.

Item Type: Article
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User: Administrator
Date Deposited: 04 Aug 2010 14:09
Last Modified: 17 Apr 2013 12:17
URI: http://eprints.bbk.ac.uk/id/eprint/1008

Archive Staff Only (login required)

Edit/View Item Edit/View Item