Visualization of macromolecular structures
O'Donoghue, S.I. and Goodsell, D.S. and Frangakis, A.S. and Jossinet, F. and Laskowski, R.A. and Nilges, M. and Saibil, Helen R. and Schafferhans, A. and Wade, R.C. and Westhof, E. and Olson, A.J. (2010) Visualization of macromolecular structures. Nature Methods 7 (3(S)), S42-S55. ISSN 1548-7091.
Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
|School:||Birkbeck Schools and Departments > School of Science > Biological Sciences|
|Research Centre:||Structural Molecular Biology, Institute of (ISMB)|
|Date Deposited:||04 Aug 2010 14:09|
|Last Modified:||06 Dec 2016 11:14|
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