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Genome and proteome annotation: organization, interpretation and integration

Reeves, G.A. and Talavera, D. and Thornton, Janet M. (2009) Genome and proteome annotation: organization, interpretation and integration. Journal of the Royal Society - Interface 6 (31), pp. 129-147. ISSN 1742-5689.

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Official URL: http://dx.doi.org/10.1098/rsif.2008.0341

Abstract

Recent years have seen a huge increase in the generation of genomic and proteomic data. This has been due to improvements in current biological methodologies, the development of new experimental techniques and the use of computers as support tools. All these raw data are useless if they cannot be properly analysed, annotated, stored and displayed. Consequently, a vast number of resources have been created to present the data to the wider community. Annotation tools and databases provide the means to disseminate these data and to comprehend their biological importance. This review examines the various aspects of annotation: type, methodology and availability. Moreover, it puts a special interest on novel annotation fields, such as that of phenotypes, and highlights the recent efforts focused on the integrating annotations.

Item Type: Article
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User: Administrator
Date Deposited: 04 Aug 2010 14:09
Last Modified: 17 Apr 2013 12:17
URI: http://eprints.bbk.ac.uk/id/eprint/1112

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