Enhanced ERPs to visual stimuli in unaffected male siblings of ASD children
Anzures, G. and Goyet, L. and Ganea, N. and Johnson, Mark H. (2016) Enhanced ERPs to visual stimuli in unaffected male siblings of ASD children. Child Neuropsychology 22 (2), pp. 220-237. ISSN 0929-7049.
Autism spectrum disorders are characterized by deficits in social and communication abilities. While unaffected relatives lack severe deficits, milder impairments have been reported in some first-degree relatives. The present study sought to verify whether mild deficits in face perception are evident among the unaffected younger siblings of children with ASD. Children between 6–9 years of age completed a face-recognition task and a passive viewing ERP task with face and house stimuli. Sixteen children were typically developing with no family history of ASD, and 17 were unaffected children with an older sibling with ASD. Findings indicate that, while unaffected siblings are comparable to controls in their face-recognition abilities, unaffected male siblings in particular show relatively enhanced P100 and P100-N170 peak-to-peak amplitude responses to faces and houses. Enhanced ERPs among unaffected male siblings is discussed in relation to potential differences in neural network recruitment during visual and face processing.
|Keyword(s) / Subject(s):||Face recognition, N170, ASD, Unaffected siblings, ERP|
|School:||Birkbeck Schools and Departments > School of Science > Psychological Sciences|
|Research Centre:||Brain and Cognitive Development, Centre for (CBCD)|
|Date Deposited:||30 Nov 2015 14:31|
|Last Modified:||02 Dec 2016 11:44|
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