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A twin study investigating the genetic and environmental aetiologies of parent, teacher and child ratings of autistic-like traits and their overlap

Ronald, Angelica and Happé, F. and Plomin, R. (2008) A twin study investigating the genetic and environmental aetiologies of parent, teacher and child ratings of autistic-like traits and their overlap. European Child & Adolescent Psychiatry 17 (8), pp. 473-483. ISSN 1018-8827.

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Official URL: http://dx.doi.org/10.1007/s00787-008-0689-5

Abstract

In the present study we investigated phenotypic agreement between informants (parent, teacher and child self-report) on ratings of autistic-like traits and compared the genetic and environmental aetiologies of the informants’ ratings and of their covariance. Parents and teachers of >2,500 pairs from a community twin sample completed an abbreviated Childhood Asperger Syndrome Test (CAST). The twins also completed an adapted self-report version of the CAST. Structural equation model-fitting was carried out. Correlations between raters were significant but moderate (0.16–0.33). The magnitude of heritability estimates of autistic-like traits varied across raters, being highest for parent-rated autistic-like traits (82–87%) and more modest for child self-reported autistic-like traits (36–47%). Genetic overlap was significant but moderate across all raters. These findings are discussed in relation to population screening for autism and future genetic research.

Item Type: Article
Keyword(s) / Subject(s): autistic traits, autism, raters, twins, behaviour
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Psychological Sciences
Depositing User: Administrator
Date Deposited: 17 Dec 2010 10:10
Last Modified: 17 Apr 2013 12:19
URI: http://eprints.bbk.ac.uk/id/eprint/2543

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