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Molecular architecture of bacterial type IV secretion systems

Waksman, Gabriel and Fronzes, Remi (2010) Molecular architecture of bacterial type IV secretion systems. Trends in Biochemical Sciences 35 (12), pp. 691-698. ISSN 0968-0004.

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In Gram-negative bacteria, type IV secretion (T4S) systems form ATP-powered complexes that span the entire cellular envelope and secrete a wide variety of substrates from single proteins to protein-protein and protein-DNA complexes. Recent structural data, namely the electron microscopy structure of the T4S core complex and the atomic-resolution structure of its outermembrane pore, have profoundly altered our understanding of T4S architecture and mechanisms.

Item Type: Article
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User: Administrator
Date Deposited: 26 May 2011 11:23
Last Modified: 17 Apr 2013 12:20

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