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Resuscitation-promoting factors possess a lysozyme-like domain

Cohen Gonsaud, M. and Keep, Nicholas H. and Davies, A.P. and Ward, J.M. and Henderson, B. and Labesse, G. (2004) Resuscitation-promoting factors possess a lysozyme-like domain. Trends in Biochemical Sciences 29 (1), pp. 7-10. ISSN 0968-0004.


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The novel bacterial cytokine family – resuscitation-promoting factors (Rpfs) – share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain. The model highlights the good conservation of residues involved in catalysis and substrate binding. A lysozyme-like function makes sense for this domain in the light of experimental characterization of the biological function of Rpfs.

Item Type: Article
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User: Sandra Plummer
Date Deposited: 17 May 2006
Last Modified: 17 Apr 2013 12:32

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