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Synchrotron radiation circular dichroism (SRCD) spectroscopy: An emerging method in structural biology for examining protein conformations and protein interactions

Wallace, Bonnie A. and Gekko, K. and Vrønning Hoffmann, S. and Lin, Y.H. and Sutherland, J.C. and Tao, Y. and Wien, F. and Janes, R.W. (2011) Synchrotron radiation circular dichroism (SRCD) spectroscopy: An emerging method in structural biology for examining protein conformations and protein interactions. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 649 (1), pp. 177-178. ISSN 0168-9002.

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.nima.2010.10.135

Abstract

Circular dichroism (CD) spectroscopy is a well-established technique in structural biology. The use of synchrotron radiation as an intense light source for these measurements extends the applications possible using lab-based instruments. In recent years, there has been a major growth in synchrotron radiation circular dichroism (SRCD) beamlines worldwide, including ones at the NSLS, ISA, SRS, HiSOR, BSRF, NSRRC, SOLEIL, Diamond, TERAS, BESSYII, and ANKA synchrotrons. Through the coordinated efforts of beamline scientists and users at these sites, important proof-of-principle studies have been done enabling the method to be developed for novel and productive studies on biological systems. This paper describes the characteristics of SRCD beamlines and some of the new types of applications that have been undertaken using these beamlines.

Item Type: Article
Keyword(s) / Subject(s): Synchrotron radiation circular dichroism spectroscopy, protein secondary structure, conformational changes, macromolecular interactions
School or Research Centre: Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User: Administrator
Date Deposited: 26 Jul 2011 09:20
Last Modified: 17 Apr 2013 12:21
URI: http://eprints.bbk.ac.uk/id/eprint/3849

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