Chudasama, V. and Smith, M.E.B. and Schumacher, F.F. and Papaioannou, D. and Waksman, Gabriel and Baker, J.R. and Caddick, S. (2011) Bromopyridazinedione-mediated protein and peptide bioconjugation. Chemical Communications 47 (31), pp. 8781-8783. ISSN 1359-7345.
Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/c1cc12807h
Abstract
Bromopyridazinedione-mediated bioconjugation to a cysteine containing protein and a disulfide containing peptide is described. The conjugates are cleavable in an excess of thiol, including cytoplasmically-relevant concentrations of glutathione, and show a high level of hydrolytic stability. The constructs have the potential for four points of chemical attachment.
| Item Type: | Article |
|---|---|
| School or Research Centre: | Birkbeck Schools and Research Centres > School of Science > Biological Sciences |
| Depositing User: | Administrator |
| Date Deposited: | 12 Aug 2011 11:17 |
| Last Modified: | 17 Apr 2013 12:21 |
| URI: | http://eprints.bbk.ac.uk/id/eprint/4043 |
Archive Staff Only (login required)
 |
Edit/View Item |
