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The use of botulinum toxin in the treatment of adductor spasmodic dysphonia

Whurr, R. and Lorch, Marjorie and Fontana, H. and Brookes, G.B. and Lees, A.J. and Marsden, C.D. (1993) The use of botulinum toxin in the treatment of adductor spasmodic dysphonia. Journal of Neurology, Neurosurgery & Psychiatry 56 (5), pp. 526-530. ISSN 0022-3050.

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Botulinum toxin injections have been used to treat 31 patients with adductor spasmodic dysphonia. Injections of 3.00-3.75 units of botulinum toxin were performed bilaterally into the thyroarytenoid muscle. This treatment significantly decreased the standard deviation of the fundamental frequency of the speech sample, indicating a reduction in the variability of pitch amongst patients. A total of 96% of patients' subjective diary reports showed an improvement with a median of 7 days to peak effect and a 5 week duration of peak effect.

Item Type: Article
School or Research Centre: Birkbeck Schools and Research Centres > School of Social Sciences, History and Philosophy > Applied Linguistics and Communication
Depositing User: Administrator
Date Deposited: 27 Sep 2011 10:42
Last Modified: 11 Oct 2016 13:48

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