Chaperone-usher pathways: diversity and pilus assembly mechanism
Busch, Andreas and Waksman, Gabriel (2012) Chaperone-usher pathways: diversity and pilus assembly mechanism. Philosophical Transactions of the Royal Society B: Biological Sciences 367 (1592), pp. 1112-1122. ISSN 0962-8436.
Up to eight different types of secretion systems, and several more subtypes, have been described in Gram-negative bacteria. Here, we focus on the diversity and assembly mechanism of one of the best-studied secretion systems, the widespread chaperone–usher pathway known to assemble and secrete adhesive surface structures, called pili or fimbriae, which play essential roles in targeting bacterial pathogens to the host.
|Keyword(s) / Subject(s):||chaperone–usher, pilus biogenesis, host–pathogen interactions|
|School:||Birkbeck Schools and Departments > School of Science > Biological Sciences|
|Research Centre:||Structural Molecular Biology, Institute of (ISMB)|
|Date Deposited:||19 Mar 2012 09:10|
|Last Modified:||06 Dec 2016 10:46|
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