RIBFIND: a web server for identifying rigid bodies in protein structures and to aid flexible fitting into cryo EM maps

Pandurangan, Arun and Topf, Maya (2012) RIBFIND: a web server for identifying rigid bodies in protein structures and to aid flexible fitting into cryo EM maps. Bioinformatics 28 (18), pp. 2391-2393. ISSN 1367-4803.

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Abstract

Motivation: To better analyze low-resolution cryo electron microscopy maps of macromolecular assemblies, component atomic structures frequently have to be flexibly fitted into them. Reaching an optimal fit and preventing the fitting process from getting trapped in local minima can be significantly improved by identifying appropriate rigid bodies in the fitted component. Results: Here we present the RIBFIND server, a tool for identifying rigid bodies in protein structures. The server identifies rigid bodies in proteins by calculating spatial proximity between their secondary structural elements. Availability: The RIBFIND web server and its standalone program are available at http://ribfind.ismb.lon.ac.uk.

Item Type:	Article
School or Research Centre:	Birkbeck Schools and Research Centres > School of Science > Biological Sciences
Depositing User:	Administrator
Date Deposited:	18 Jul 2012 13:30
Last Modified:	08 May 2013 09:22
URI:	http://eprints.bbk.ac.uk/id/eprint/4980

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