BIROn - Birkbeck Institutional Research Online

    What causes internalising traits and autistic traits to co-occur in adolescence? A community-based twin study

    Scherff, Aline and Taylor, M. and Eley, T.C. and Happé, F. and Charman, T. and Ronald, Angelica (2014) What causes internalising traits and autistic traits to co-occur in adolescence? A community-based twin study. Journal of Abnormal Child Psychology 42 (4), pp. 601-610. ISSN 0091-0627.

    Full text not available from this repository.

    Abstract

    Autism shows a high degree of comorbidity with anxiety disorders. Adolescence is a time of increased stress and vulnerability to internalising problems. This study addresses for the first time the degree of genetic and environmental overlap between autistic traits (total measure and subscales) and internalising traits in a community-based adolescent twin sample. Parents of 12-14-year-old twins (N = 3,232 pairs; 3,460 males, 3,004 females) reported on the twins’ internalising and autistic traits. Autistic trait subscales were created using principal component analysis. Bivariate twin model-fitting was conducted. Autistic and internalising traits correlated moderately (r = 0.30). Genetic influences on individual traits were substantial but genetic overlap between traits was moderate (genetic correlation: males = 0.30, females = 0.12). Shared environmental influences were low for internalising traits and moderate for autistic traits, and showed considerable overlap (shared environmental correlation: males = 0.53, females = 1). Nonshared environmental influences were moderate for internalising traits and low for autistic traits and showed low overlap. A multiple component solution was found for autistic traits and of the derived subscales, autistic-like ‘Social Unease’ showed the most phenotypic and genetic overlap with internalising traits.

    Metadata

    Item Type: Article
    Keyword(s) / Subject(s): Adolescence, Autistic disorder, Comorbidity, Genetics, Internalising disorders
    School: Birkbeck Schools and Departments > School of Science > Psychological Sciences
    Research Centre: Brain and Cognitive Development, Centre for (CBCD)
    Depositing User: Administrator
    Date Deposited: 02 Sep 2013 09:19
    Last Modified: 02 Dec 2016 11:55
    URI: http://eprints.bbk.ac.uk/id/eprint/8073

    Statistics

    Downloads
    Activity Overview
    0Downloads
    0Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item