BIROn - Birkbeck Institutional Research Online

    Structural organisation of the type IV secretion systems

    Waksman, Gabriel and Orlova, Elena (2014) Structural organisation of the type IV secretion systems. Current Opinion in Microbiology 17 , pp. 24-31. ISSN 1369-5274.

    [img]
    Preview
    Text
    8802.pdf - Published Version of Record
    Available under License Creative Commons Attribution Non-commercial No Derivatives.

    Download (3MB) | Preview

    Abstract

    Type IV secretion (T4S) systems are large dynamic nanomachines that transport DNAs and/or proteins through the membranes of bacteria. Because of their complexity and multi-protein organisation, T4S systems have been extremely challenging to study structurally. However in the past five years significant milestones have been achieved by X-ray crystallography and cryo-electron microscopy. This review describes some of the more recent advances: the structures of some of the protein components of the T4S systems and the complete core complex structure that was determined using electron microscopy.

    Metadata

    Item Type: Article
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Research Centre: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 09 Dec 2013 15:59
    Last Modified: 06 Dec 2016 10:46
    URI: http://eprints.bbk.ac.uk/id/eprint/8802

    Statistics

    Downloads
    Activity Overview
    159Downloads
    80Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item