BIROn - Birkbeck Institutional Research Online

    Developmental pathways to autism: a review of prospective studies of infants at risk

    Jones, Emily and Gliga, Teodora and Bedford, Rachael and Charman, T. and Johnson, Mark H. (2014) Developmental pathways to autism: a review of prospective studies of infants at risk. Neuroscience & Biobehavioral Reviews 39 , pp. 1-33. ISSN 0149-7634.

    [img]
    Preview
    Text
    8960.pdf - Published Version
    Available under License Creative Commons Attribution Non-commercial No Derivatives.

    Download (2MB) | Preview

    Abstract

    Autism Spectrum Disorders (ASDs) are neurodevelopmental disorders characterized by impairments in social interaction and communication, and the presence of restrictive and repetitive behaviors. Symptoms of ASD likely emerge from a complex interaction between pre-existing neurodevelopmental vulnerabilities and the child's environment, modified by compensatory skills and protective factors. Prospective studies of infants at high familial risk for ASD (who have an older sibling with a diagnosis) are beginning to characterize these developmental pathways to the emergence of clinical symptoms. Here, we review the range of behavioral and neurocognitive markers for later ASD that have been identified in high-risk infants in the first years of life. We discuss theoretical implications of emerging patterns, and identify key directions for future work, including potential resolutions to several methodological challenges for the field. Mapping how ASD unfolds from birth is critical to our understanding of the developmental mechanisms underlying this disorder. A more nuanced understanding of developmental pathways to ASD will help us not only to identify children who need early intervention, but also to improve the range of interventions available to them.

    Metadata

    Item Type: Article
    School: Birkbeck Schools and Departments > School of Science > Psychological Sciences
    Research Centre: Brain and Cognitive Development, Centre for (CBCD)
    Depositing User: Administrator
    Date Deposited: 14 Jan 2014 13:46
    Last Modified: 02 Dec 2016 11:44
    URI: http://eprints.bbk.ac.uk/id/eprint/8960

    Statistics

    Downloads
    Activity Overview
    266Downloads
    146Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item