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    Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies

    Bhatti, M. and McHugh, T. and Milanesi, Lilia and Tomas, Salvador (2014) Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies. Chemical Communications 50 , pp. 7649-7651. ISSN 1359-7345.

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    Abstract

    A self-assembled nanoparticle containing a photosensitizer and a Trojan-horse moiety (cholesterol), binds an anti-TB pro-drug and increases 1000-fold its activity against mycobacteria. These minimalist constructs will allow development of economically viable, efficient drug preparations for the treatment of drug-resistant TB infections.

    Metadata

    Item Type: Article
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Research Centre: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 27 May 2014 07:13
    Last Modified: 06 Dec 2016 10:38
    URI: http://eprints.bbk.ac.uk/id/eprint/9787

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