From early markers to neuro-developmental mechanisms of autism
Gliga, Teodora and Jones, Emily and Bedford, R. and Charman, T. and Johnson, Mark H. (2014) From early markers to neuro-developmental mechanisms of autism. Developmental Review 34 (189), pp. 189-207. ISSN 0273-2297.
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A fast growing field, the study of infants at risk because of having an older sibling with autism (i.e. infant sibs) aims to identify the earliest signs of this disorder, which would allow for earlier diagnosis and intervention. More importantly, we argue, these studies offer the opportunity to validate existing neuro-developmental models of autism against experimental evidence. Although autism is mainly seen as a disorder of social interaction and communication, emerging early markers do not exclusively reflect impairments of the “social brain”. Evidence for atypical development of sensory and attentional systems highlight the need to move away from localized deficits to models suggesting brain-wide involvement in autism pathology. We discuss the implications infant sibs findings have for future work into the biology of autism and the development of interventions.
|Keyword(s) / Subject(s):||Infants, Autism, The “social brain”, Sensory processing|
|School:||Birkbeck Schools and Departments > School of Science > Psychological Sciences|
|Research Centre:||Brain and Cognitive Development, Centre for (CBCD)|
|Date Deposited:||13 Jun 2014 08:27|
|Last Modified:||02 Dec 2016 11:44|
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