June 2009

Ekeowa, U.I. and Gooptu, Bibek and Belorgey, D. and Hägglöf, P. and Karlsson‑Li, S. and Miranda, E. and Pérez, J. and MacLeod, I. and Kroger, H. and Marciniak, S.J. and Crowther, D.C. and Lomas, D.A. (2009) α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clinical Science 116 (12), pp. 837-850. ISSN 0143-5221.

1 August 2009

Gooptu, Bibek and Ekeowa, U.I. and Lomas, D.A. (2009) Mechanisms of emphysema in 1-antitrypsin deficiency: molecular and cellular insights. European Respiratory Journal 34 (2), pp. 475-488. ISSN 0903-1936.

September 2010

Miranda, E. and Pérez, J. and Ekeowa, U.I. and Hadzic, N. and Kalsheker, N. and Gooptu, Bibek and Portmann, B. and Belorgey, D. and Hill, M. and Chambers, S. and Teckman, J. and Alexander, G.J. and Marciniak, S.J. and Lomas, D.A. (2010) A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency. Hepatology 52 (3), pp. 1078-1088. ISSN 0270-9139.

October 2010

Ekeowa, U.I. and Freeke, J. and Miranda, E. and Gooptu, Bibek and Bush, M.F. and Pérez, J. and Teckman, J. and Robinson, C.V. and Lomas, D.A. (2010) Defining the mechanism of polymerization in the serpinopathies. Proceedings of the National Academy of Sciences of the United States of America 107 (40), pp. 17146-17151. ISSN 0027-8424.

4 December 2011

Irving, J.A. and Ekeowa, U.I. and Belorgey, D. and Haq, I. and Gooptu, Bibek and Miranda, E. and Pérez, J. and Roussel, B.D. and Ordóñez, A. and Dalton, L.E. and Thomas, S.E. and Marciniak, S.J. and Parfrey, H. and Chilvers, E.R. and Teckman, J.H. and Alam, S. and Mahadeva, R. and Rashid, S.T. and Vallier, L. and Lomas, D.A. (2011) The serpinopathies: studying serpin polymerization in vivo. In: Whisstock, J.C. and Bird, P. I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 421-466. ISBN 9780123859501.

5 December 2011

Chang, Y.-P. and Mahadeva, R. and Patschull, A.O.M. and Nobeli, Irene and Ekeowa, U.I. and McKay, A.R. and Thalassinos, Konstantinos and Irving, J.A. and Haq, I. and Nyon, Mun Peak and Christodoulou, John and Ordóñez, A. and Miranda, E. and Gooptu, Bibek (2011) Targeting serpins in high-throughput and structure-based drug design. In: Whisstock, J.C. and Bird, P.I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 139-175. ISBN 9780123859501.

7 March 2012

Nyon, Mun Peak and Segu, Lakshmi and Cabrita, L.D. and Lévy, Géraldine R. and Kirkpatrick, J. and Roussel, B.D. and Patschull, Anathe O.M. and Barrett, Tracey E. and Ekeowa, U.I. and Kerr, R. and Waudby, Christopher A. and Kalsheker, N. and Hill, M. and Thalassinos, Konstantinos and Lomas, D.A. and Christodoulou, John and Gooptu, Bibek (2012) Structural dynamics associated with intermediate formation in an archetypal conformational disease. Structure 20 (3), pp. 504-512. ISSN 0969-2126.