Article

Haq, I. and Irving, J. and Saleh, A.D. and Dron, L. and Regan-Mochrie, G.L. and Motamedi-Shad, N. and Hurst, J.R. and Gooptu, Bibek and Lomas, D.A. (2016) Deficiency mutations of α1-antitrypsin differentially affect folding, function and polymerization. American Journal of Respiratory Cell and Molecular Biology 54 (1), pp. 71-80. ISSN 1044-1549.

Nyon, M.P. and Prentice, T. and Day, J. and Kirkpatrick, J. and Sivalingam, G.N. and Lévy, Géraldine R. and Haq, I. and Irving, J. and Lomas, D.A. and Christodoulou, John and Gooptu, Bibek and Thalassinos, Konstantinos (2015) An integrative approach combining ion mobility mass spectrometry, X-ray crystallography and NMR spectroscopy to study the conformational dynamics of α1-antitrypsin upon ligand binding. Protein Science 24 (8), pp. 1301-1312. ISSN 0961-8368.

Nyon, M.P. and Prentice, T. and Day, J. and Kirkpatrick, J. and Sivalingam, G.N. and Levy, G. and Haq, I. and Irving, J.A. and Lomas, D.A. and Christodoulou, John and Gooptu, Bibek and Thalassinos, Konstantinos (2015) An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1-antitrypsin upon ligand binding. Protein Science 24 (8), pp. 1301-1312. ISSN 0961-8368.

Tan, L. and Perez, J. and Mela, M. and Miranda, E. and Burling, K.A. and Rouhani, F.N. and DeMeo, D.L. and Haq, I. and Irving, J.A. and Ordóñez, A. and Dickens, J.A. and Brantly, M. and Marciniak, S.J. and Alexander, G.J. and Gooptu, Bibek and Lomas, D.A. (2015) Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody. The International Journal of Biochemistry & Cell Biology 58 , pp. 81-91. ISSN 1357-2725.

Haq, I. and Irving, J.A. and Faull, S.V. and Dickens, J.A. and Ordóñez, A. and Belorgey, D. and Gooptu, Bibek and Lomas, D.A. (2013) Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway. Bioscience Reports 33 (3), pp. 499-511. ISSN 0144-8463.

Book Section

Chang, Y.-P. and Mahadeva, R. and Patschull, A.O.M. and Nobeli, Irene and Ekeowa, U.I. and McKay, A.R. and Thalassinos, Konstantinos and Irving, J.A. and Haq, I. and Nyon, Mun Peak and Christodoulou, John and Ordóñez, A. and Miranda, E. and Gooptu, Bibek (2011) Targeting serpins in high-throughput and structure-based drug design. In: Whisstock, J.C. and Bird, P.I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 139-175. ISBN 9780123859501.

Irving, J.A. and Ekeowa, U.I. and Belorgey, D. and Haq, I. and Gooptu, Bibek and Miranda, E. and Pérez, J. and Roussel, B.D. and Ordóñez, A. and Dalton, L.E. and Thomas, S.E. and Marciniak, S.J. and Parfrey, H. and Chilvers, E.R. and Teckman, J.H. and Alam, S. and Mahadeva, R. and Rashid, S.T. and Vallier, L. and Lomas, D.A. (2011) The serpinopathies: studying serpin polymerization in vivo. In: Whisstock, J.C. and Bird, P. I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 421-466. ISBN 9780123859501.