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    Number of items: 100.

    A

    Ahn, M. and Hagan, C.L. and Bernardo-Gancedo, A. and De Genst, E. and Newby, F.N. and Christodoulou, John and Dhulesia, A. and Dumoulin, M. and Robinson, C.V. and Dobson, C.M. and Kumita, J.R. (2016) The significance of the location of mutations for the native-state dynamics of human Lysozyme. Biophysical Journal 111 (11), pp. 2358-2367. ISSN 0006-3495.

    Amaning Danquah, C. and Maitra, Arundhati and Gibbons, S. and Nicklin, Jane and Bhakta, Sanjib (2016) HT-SPOTi: a rapid Drug Susceptibility Test (DST) to evaluate antibiotic resistance profiles and novel chemicals for anti-infective drug discovery. Current Protocols in Microbiology 40 , ISSN 1934-8533.

    Amer, A.A.A. and Gurung, J.M. and Costa, Tiago and Ruuth, K. and Zavialov, A.V. and Forsberg, Å. and Francis, M.S. (2016) YopN and TyeA Hydrophobic Contacts Required for Regulating Ysc-Yop Type III Secretion Activity by Yersinia pseudotuberculosis. Frontiers in Cellular and Infection Microbiology 6 , ISSN 2235-2988.

    Ashford, Paul and Hernandez duran, Anna and Greco, T.M. and Buch, A. and Sodeik, B. and Cristea, I.M. and Grünewald, K. and Shepherd, Adrian J. and Topf, Maya (2016) HVint: a strategy for identifying novel protein-protein interactions in Herpes Simplex Virus Type 1. Molecular & Cellular Proteomics 15 (9), pp. 2939-2953. ISSN 1535-9476.

    B

    Baglioni, M. and Bartoletti, A. and Bozec, L. and Giorgi, R. and Odlyha, Marianne and Pianorsi, D. and Poggi, G. and Baglioni, P. (2016) Nanomaterials for the cleaning and pH adjustment of vegetable tanned leather. Applied Physics A 122 (2), pp. 1-11. ISSN 0947-8396.

    Baratchian, M. and Davis, C.A. and Shimizu, A. and Escors, D. and Bagneris, Claire and Barrett, Tracey E. and Collins, M.K. (2016) Distinct activation mechanisms of NF-κB regulator inhibitor of NF-κB Kinase (IKK) by isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP)*. Journal of Biological Chemistry 291 , pp. 7608-7620. ISSN 0021-9258.

    Bhakta, Sanjib (2016) Design and synthesis of 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine (SQ109) pyrrole hybrid derivatives: discovery of potent anti-tubercular agents effective against multi-drug resistant mycobacteria. Journal of Medicinal Chemistry 59 (6), pp. 2780-2793. ISSN 0022-2623.

    Bhakta, Sanjib and Guzman, Juan David and Evangelopoulos, Dimitrios and Munshi, Tulika and Mcmahon, Eleanor (2016) DNA sequence-selective C8-linked pyrrolobenzodiazepine(PBD)-heterocyclic polyamide conjugates show anti-tubercular specific activities. The Journal of Antibiotics 69 , pp. 843-849. ISSN 0021-8820.

    Bokori-Brown, M. and Martin, T.G. and Naylor, Claire and Basak, Ajit K. and Titball, R.W. and Savva, Christos (2016) Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein. Nature Communications 7 , p. 11293. ISSN 2041-1723.

    Bokori-Brown, M. and Petrov, P.G. and Khafaji, M.A. and Mughal, M.K. and Naylor, Claire and Shore, A.C. and Gooding, K.M. and Casanova, F. and Mitchell, T.J. and Titball, R.W. and Winlove, C.P. (2016) Red blood cell susceptibility to pneumolysin: Correlation with membrane biochemical and physical properties. Journal of Biological Chemistry 291 (19), pp. 10210-10227. ISSN 0021-9258.

    Britto, M. and Goulet, A. and Rizvi, S. and von Loeffelholz, O. and Moores, Carolyn A. and Cross, R.A. (2016) Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proceedings of the National Academy of Sciences of the United States of America 113 (47), E7483-E7489. ISSN 0027-8424.

    Brucoli, F. and Guzman, Juan David and Basher, M.A. and Evangelopoulos, Dimitrios and Mcmahon, Eleanor and Munshi, Tulika and McHugh, T.D. and Fox, K.R. and Bhakta, Sanjib (2016) DNA sequence-selective C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates show anti-tubercular-specific activities. The Journal of Antibiotics 69 , pp. 843-849. ISSN 0021-8820.

    Bullock, Joshua and Schwab, J. and Thalassinos, Kostas and Topf, Maya (2016) The importance of non-accessible crosslinks and solvent accessible surface distance in modelling proteins with restraints from crosslinking mass spectrometry. Molecular & Cellular Proteomics 15 (7), pp. 2491-2500. ISSN 1535-9476.

    C

    Cabreiro, Filipe (2016) Metformin joins forces with microbes. Cell Host & Microbe 19 (1), pp. 1-3. ISSN 1931-3128.

    Cabrita, Lisa D. and Cassaignau, Anaïs M.E. and Launay, Hélène M.M. and Waudby, Christopher A. and Wlodarski, Tomasz and Camilloni, C. and Karyadi, Maria-Evangelia and Robertson, Amy L. and Wang, Xiaolin and Wentink, Anne S. and Goodsell, Luke S. and Woolhead, C.A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2016) A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding. Nature Structural & Molecular Biology 23 (4), pp. 278-285. ISSN 1545-9993.

    Carroni, Marta and Saibil, Helen R. (2016) Cryo electron microscopy to determine the structure of macromolecular complexes. Methods 95 , pp. 78-85. ISSN 1046-2023.

    Cassaignau, A.M. and Launay, H.M. and Karyadi, M.E. and Wang, X. and Waudby, C.A. and Deckert, A. and Robertson, A.L. and Cabrita, Lisa and Christodoulou, John (2016) A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy. Nature Protocols 11 , pp. 1492-1507. ISSN 1754-2189.

    Chandrashekhar Lele, A. and Amarnath Mishra, D. and Karmila Kamil, T. and Bhakta, Sanjib and Sohel Degani, M. (2016) Repositioning of DHFR Inhibitors. Current Topics In Medicinal Chemistry 16 (19), pp. 2125-2143. ISSN 1568-0266.

    Chin, S. and Yang, D. and Miles, Andrew and Eckford, P.D.W. and Molinski, S. and Wallace, Bonnie A. and Bear, C.E. (2016) Attenuation of Phosphorylation-dependent activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by disease-causing mutations at the transmission interface. Journal of Biological Chemistry 292 (5), pp. 1988-1999. ISSN 0021-9258.

    Colledge, Matthew and Wallace, Bonnie A. (2016) AnglerFish: a webserver for defining the geometry of α-Helices in membrane proteins. Bioinformatics , btw781. ISSN 1367-4803.

    Cossé, M.M. and Hayward, Richard and Subtil, A. (2016) One face of Chlamydia trachomatis: the infectious elementary body. In: UNSPECIFIED (ed.) Current Topics in Microbiology and Immunology. Berlin, Germany: Springer. (In Press)

    Costa, Tiago and Ilangovan, Aravindan and Ukleja, Marta and Redzej, Adam and Santini, Joanne and Smith, T.K. and Egelman, E.H. and Waksman, Gabriel (2016) Structure of the Bacterial Sex F Pilus reveals an assembly of a Stoichiometric Protein-Phospholipid Complex. Cell 166 (6), 1436-1444.e10. ISSN 0092-8674.

    Czarnecki, Jan and Shepherd, Adrian J. (2016) Metabolic pathway mining. In: Keith, J.M. (ed.) Bioinformatics Volume II: Structure, Function, and Applications. Methods in Molecular Biology 1526. New York, U.S.: Humana Press, pp. 139-158. ISBN 9781493966110.

    D

    D'Auria, S. and Lopes, J.L.S. and Yoneda, Juliana and Martins, J.M. and DeMarco, R. and Jameson, D.M. and Castro, A.M. and Bossolan, N.R.S. and Wallace, Bonnie A. and Araujo, A.P.U. (2016) Environmental factors modulating the stability and enzymatic activity of the Petrotoga mobilis Esterase (PmEst). PLoS One 11 (6), e0158146. ISSN 1932-6203.

    Deckert, Annika and Waudby, Christopher and Wlodarski, Tomasz and Wentink, Anne and Wang, Xiaolin and Kirkpatrick, John and Paton, Jack and Camilloni, C. and Kukic, P. and Dobson, C.M. and Vendruscolo, M. and Cabrita, Lisa and CHRISTODOULOU, JOHN (2016) Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor. Proceedings of the National Academy of Sciences of the United States of America 113 (18), pp. 5012-5017. ISSN 0027-8424.

    Densham, R. and Garvin, A. and Keep, Nicholas H. and Watts, F. and Morris, J. and Et, al (2016) Human BRCA1-BARD1 Ubiquitin ligase activity counters chromatin barriers to DNA resection. Nature Structural & Molecular Biology 23 , pp. 647-655. ISSN 1545-9993.

    Denyer, Michael P. and Pinheiro, D.Y. and Garden, O.A. and Shepherd, Adrian J. (2016) Missed, not missing: Phylogenomic evidence for the existence of Avian FoxP3. PLoS One 11 (3), e0150988. ISSN 1932-6203.

    Drew, Elliott and Jones, D.T. and Wallace, Bonnie A. (2016) Protein design for decreased disorder: SHERP as an exemplar protein. Biophysical Journal 110 (3), 555a. ISSN 0006-3495.

    Dumoux, Maud and Hayward, Richard (2016) Membrane contact sites between pathogen-containing compartments and host organelles. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1861 (8(B)), pp. 895-899. ISSN 1388-1981.

    de la Guardia, Y. and Gilliat, A.F. and Hellberg, J. and Rennert, P. and Cabreiro, Filipe and Gems, D. (2016) Run-on of germline apoptosis promotes gonad senescence in C. elegans. Oncotarget 7 (26), ISSN 1949-2553.

    F

    Flierman, D. and van der Heden van Noort, G.J. and Ekkebus, R. and Geurink, P.P. and Mevissen, T.E.T. and Hospenthal, Manuela and Komander, D. and Ovaa, H. (2016) Non-hydrolyzable Diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 Pockets. Cell Chemical Biology 23 (4), pp. 472-482. ISSN 2451-9456.

    Flores-Díaz, M. and Monturiol-Gross, L. and Naylor, Claire and Alape-Girón, A. and Flieger, A. (2016) Bacterial Sphingomyelinases and Phospholipases as virulence factors. Microbiology and Molecular Biology Reviews 80 (3), pp. 597-628. ISSN 1092-2172.

    Francis, M.S. and Amer, A.A.A. and Milton, D.L. and Costa, Tiago (2016) Site-directed mutagenesis and its application in studying the interactions of T3S components. In: Niles, M.L. and Condry, D. (eds.) Type 3 Secretion Systems: Methods and Protocols. Methods in Molecular Biology 1531. New York, U.S.: Humana Press, pp. 11-31. ISBN 9781493966479.

    G

    Gabreski, N.A. and Vaghasia, J.K. and Novakova, S.S. and Mcdonald, Neil and Pierchala, B.A. (2016) Exon Skipping in theRETGene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction. Journal of Biological Chemistry 291 (31), pp. 16249-16262. ISSN 0021-9258.

    H

    Haq, I. and Irving, J. and Saleh, A.D. and Dron, L. and Regan-Mochrie, G.L. and Motamedi-Shad, N. and Hurst, J.R. and Gooptu, Bibek and Lomas, D.A. (2016) Deficiency mutations of α1-antitrypsin differentially affect folding, function and polymerization. American Journal of Respiratory Cell and Molecular Biology 54 (1), pp. 71-80. ISSN 1044-1549.

    Haq, Imran and Irving, James and Saleh, A.D. and Dron, L. and Regan-Mochrie, G.L. and Motamedi-Shad, Neda and Hurst, J.R. and Gooptu, Bibekbrata and Lomas, David (2016) Deficiency mutations of Alpha-1 Antitrypsin. Effects on folding, function, and polymerization. American Journal of Respiratory Cell and Molecular Biology 54 (1), pp. 71-80. ISSN 1044-1549.

    Harvey, D.J. and Scarff, C.A. and Edgeworth, M. and Struwe, W.B. and Pagel, K. and Thalassinos, Kostas and Crispin, M. and Scrivens, J. (2016) Travelling-wave ion mobility and negative ion fragmentation of high-mannoseN-glycans. Journal of Mass Spectrometry 51 (3), pp. 219-235. ISSN 1076-5174.

    Hemming, Joanna M. and Hughes, Brian R. and Rennie, A. and Tomas, Salvador and Campbell, R. and Hughes, A. and Arnold, T. and Botchway, S. and Thompson, Katherine C. (2016) Environmental pollutant ozone causes damage to lung surfactant protein B, SP-B. Biochemistry 54 (33), pp. 5185-5197. ISSN 0006-2960.

    Hodel, A.W. and Leung Shin Cheung, Carl and Dudkina, Natalia and Saibil, Helen R. and Hoogenboom, B.W. (2016) Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins. Current Opinion in Structural Biology 39 (1), pp. 8-15. ISSN 0959-440X.

    Hospenthal, M.K. and Redzej, A. and Dodson, K. and Ukleja, M. and Frenz, B. and Rodrigues, C. and Hultgren, S.J. and DiMaio, F. and Egelman, E.H. and Waksman, Gabriel (2016) Structure of a Chaperone-Usher Pilus reveals the molecular basis of rod uncoiling. Cell 164 , pp. 269-278. ISSN 0092-8674.

    J

    Jeremy, G. and Stevens, J. and Lowe, Alan (2016) Single-molecule imaging to characterise the transport mechanism of the Nuclear Pore Complex. In: Leake, M.C. (ed.) Chromosome Architecture: Methods and Protocols. Methods in Molecular Biology 1431. New York, U.S.: Springer New York, pp. 17-35. ISBN 9781493936298.

    Joseph, Agnal Praveen and Malhotra, S. and Burnley, T. and Wood, C. and Clare, D.K. and Winn, M. and Topf, Maya (2016) Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment. Methods 100 , pp. 42-49. ISSN 1046-2023.

    Joseph, Agnel P. and Swapna, L.S. and Rakesh, R. and Srinivasan, N. (2016) Use of evolutionary information in the fitting of atomic level protein models in low resolution cryo-EM map of a protein assembly improves the accuracy of the fitting. Journal of Structural Biology 195 (3), pp. 294-305. ISSN 1047-8477.

    K

    Kalscheuer, V.M. and James, V.M. and Himelright, M.L. and Long, P. and Oegema, R. and Jensen, C. and Bienek, M. and Hu, H. and Haas, S.A. and Topf, Maya and Hoogeboom, A.J.M. and Harvey, K. and Walikonis, R. and Harvey, R.J. (2016) Novel Missense Mutation A789V in IQSEC2 underlies X-Linked intellectual disability in the MRX78 family. Frontiers in Molecular Neuroscience 8 , ISSN 1662-5099.

    Ke, S. and Wallace, Bonnie A. and Ulmschneider, J.P. and Ulmschneider, M.B. (2016) Molecular dynamics simulations of the open state structure of a Bacterial Voltage-Gated Sodium Channel reveal the binding mechanisms of channel blockers. Biophysical Journal 110 (3), 108a. ISSN 0006-3495.

    Kearns, Sinead and Lurz, R. and Orlova, Elena and Okorokov, A.L. (2016) Two p53 tetramers bind one consensus DNA response element. Nucleic Acids Research 44 (13), pp. 6185-6199. ISSN 0305-1048.

    Kerai, L.V. and Hilton, S. and Maugueret Minerve, Tafie and Kazi, Bilkis Banu and Nicklin, Jane and Bhakta, Sanjib and Murdan, S. (2016) UV-curable gels as topical nail medicines: in vivo residence, anti-fungal efficacy and influence of gel components on their properties. International Journal of Pharmaceutics 514 (1), pp. 244-254. ISSN 0378-5173.

    L

    Lang, J. and Marechal, Amandine and Couture, M. and Santolini, J. (2016) Reaction intermediates and molecular mechanism of Peroxynitrite activation by NO synthases. Biophysical Journal 111 (10), pp. 2099-2109. ISSN 0006-3495.

    Lang, Peter F. and Smith, Barry C. (2016) Measurement and calculation of ionisation energies of atoms. Journal of Basic and Applied Research International 15 (4), pp. 301-308. ISSN 2395-3438.

    Langan, P.S. and Vandavasi, V.G. and Weiss, K. and Cooper, Jonthan B. and Ginell, S.L. and Coates, L. (2016) The structure of Toho1 β-lactamase in complex with penicillin reveals the role of Tyr105 in substrate recognition. FEBS Open Bio 6 (12), pp. 1170-1177. ISSN 2211-5463.

    Lees, William and Shepherd, Adrian J. (2016) Studying antibody repertoires with next-generation sequencing. In: Keith, J.M. (ed.) Bioinformatics. Methods in Molecular Biology 1526. New York, U.S.: Humana Press, pp. 257-270. ISBN 9781493966110.

    Lomas, D.A. and Hurst, J.R. and Gooptu, Bibekbrata (2016) Update on alpha-1 antitrypsin deficiency: new therapies. Journal of Hepatology 65 (2), pp. 413-424. ISSN 0168-8278.

    Lopes, J.L.S. and Miles, A.J. and Whitmore, L. and Wallace, Bonnie A. (2016) Spectral properties of “Disordered” and Polyproline II structures defined by Circular Dichroism Spectroscopy. Biophysical Journal 110 (3), 559a-560a. ISSN 0006-3495.

    Lopez-Fontal, Elkin and Milanesi, Lilia and Tomas, Salvador (2016) Multivalence cooperativity leading to “all-or-nothing” assembly: the case of nucleation-growth in supramolecular polymers. Chemical Science 7 (7), pp. 4468-4475. ISSN 2041-6520.

    Lukoyanova, N. and Hoogenboom, B.W. and Saibil, Helen R. (2016) The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins. Journal of Cell Science 129 (11), pp. 2125-2133. ISSN 0021-9533.

    M

    Mackay, Alan (2016) But how do atoms think? Structural Chemistry , ISSN 1040-0400.

    Maitra, Arundhati and Bates, S. and Shaik, M. and Evangelopoulos, Dimitrios and Abubakar, I. and McHugh, T.D. and Lipman, M. and Bhakta, Sanjib (2016) Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin 118 (1), pp. 138-148. ISSN 1471-8391.

    Maitra, Arundhati and Bhakta, Sanjib and Evangelopoulos, Dimitrios (2016) Repurposing drugs for treatment of tuberculosis (TB): a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin 118 (1), pp. 138-148. ISSN 1471-8391.

    Makhyoun, M.A. and Palmer, Rex and Soayed, A.A. and Refaat, H.M. and Basher, D.E. (2016) Synthesis, crystal structure and comparative DFT studies of a 1D Ni(II) polymeric complex of 2-Hydroxypyridine-N-oxide. Journal of Chemical Crystallography 46 (6-7), pp. 269-279. ISSN 1074-1542.

    Mcdonald, Neil (2016) RET functions as a dual-specificity kinase that requires allosteric inputs from juxtamembrane elements. Cell Reports 17 (12), pp. 3319-3332. ISSN 2211-1247.

    Mcdonald, Neil (2016) aPKC inhibition by Par3 CR3 flanking regions controls substrate access and underpins apical-junctional polarization. Developmental Cell 38 (4), pp. 384-398. ISSN 1534-5807.

    Meyer, E. and Carss, K.J and Rankin, J. and Nichols, J.M.E and Grozeva, D. and Joseph, A.P and Mencacci, N.E. and Papandreou, A. and Ng, J. and Barral, S. and Ngoh, A. and Ben-Pazi, H. and Willemsen, M.A. and Arkadir, D. and Barnicoat, A. and Bergman, H. and Bhate, S. and Boys, A. and Darin, N. and Foulds, N. and Gutowski, N. and Hills, A. and Houlden, H. and Hurst, J.A. and Israel, Z. and Kaminska, M. and Limousin, P. and Lumsden, D. and McKee, S. and Misra, S. and Mohammed, S.S. and Nakou, V. and Nicolai, J. and Nilsson, M. and Pall, H. and Peall, K.J. and Peters, G.B. and Prabhakar, P. and Reuter, M.S. and Rump, P. and Segel, R. and Sinnema, M. and Smith, M. and Turnpenny, P. and White, S.M. and Wieczorek, D. and Wiethoff, S. and Wilson, B.T. and Winter, G. and Wragg, C. and Pope, S. and Heales, S.J.H. and Morrogh, D. and Pittman, A. and Carr, L. J. and Perez-Dueñas, B. and Lin, J.-P. and Reis, A. and Gahl, W.A. and Toro, C. and Bhatia, K.P. and Wood, N.W. and Kamsteeg, E.-J. and Chong, W.K. and Gissen, P. and Topf, Maya and Dale, R.C. and Chubb, J.R. and Raymond, F.L. and Kurian, M.A. (2016) Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia. Nature Genetics 49 , pp. 223-237. ISSN 1061-4036.

    Mezaache-Aichour, S. and Haichour, N. and Guechi, A. and Nicklin, Jane and Zerroug, M. (2016) Bacteriocins contributing in Rhizospheric competition among Fluorescent Pseudomonads. Annual Research and Review in Biology 11 (4), pp. 1-9. ISSN 2347-565X.

    Miles, Andrew J. and Wallace, Bonnie A. (2016) Circular dichroism spectroscopy of membrane proteins. Chemical Society Reviews 18 , pp. 4859-4872. ISSN 0306-0012.

    Miller, Wayne and Miles, Andrew J. and Wallace, Bonnie A. (2016) Structure of the C-terminal domain of the Prokaryotic Sodium Channel Orthologue NsvBa. European Biophysics Journal with Biophysics letters 45 (8), pp. 807-814. ISSN 0175-7571.

    N

    Naylor, Claire and Bagneris, Claire and DeCaen, P.G. and Sula, A. and Scaglione, A. and Clapham, D.E. and Wallace, Bonnie A. (2016) Molecular basis of ion permeability in a voltage-gated sodium channel. Embo Journal 35 (8), pp. 820-830. ISSN 0261-4189.

    Nemecz, Á. and Prevost, Marie and Menny, A. and Corringer, P.-J. (2016) Emerging molecular mechanisms of signal transduction in Pentameric Ligand-Gated Ion Channels. Neuron 90 (3), pp. 452-470. ISSN 0896-6273.

    Newton, R. and Bowler, K.A. and Burns, E.M. and Chapman, P.J. and Fairweather, E.E. and Fritzl, S.J.R. and Goldberg, K.M. and Hamilton, N.M. and Holt, S.V. and Hopkins, G.V. and Jones, S.D. and Jordan, A.M. and Lyons, A.J. and Nikki March, H. and Mcdonald, Neil and Maguire, L.A. and Mould, D.P. and Purkiss, A.G. and Small, H.F. and Stowell, A.I.J. and Thomson, G.J. and Waddell, I.D. and Waszkowycz, B. and Watson, A.J. and Ogilvie, D.J. (2016) The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity. European Journal of Medicinal Chemistry 112 , pp. 20-32. ISSN 0223-5234.

    Northey, Thomas and Venthur, H. and De Biasio, F. and Chauviac, Francois-Xavier and Cole, Ambrose and Lisboa Ribeiro Junior, K.A. and Grossi, G. and Falabella, P. and Field, L.M. and Keep, Nicholas H. and Zhou, J.J. (2016) Crystal structures and binding dynamics of Odorant-Binding Protein 3 from two aphid species Megoura viciae and Nasonovia ribisnigri. Scientific Reports 6 , p. 24739. ISSN 2045-2322.

    O

    Oberoi, J. and Dunn, D. and Woodford, M. and Mariotti, L. and Schulman, J. and Bourboulia, D. and Mollapour, M. and Vaughan, Cara K. (2016) Structural and functional basis of protein phosphatase 5 substrate specificity. Proceedings of the National Academy of Sciences of the United States of America 113 (32), pp. 9009-9014. ISSN 0027-8424.

    Oliver, K.V. and Marechal, Amandine and Rich, P.R. (2016) Effects of the hydration state on the mid-infrared spectra of urea and creatinine in relation to urine analyses. Applied Spectroscopy 70 (6), pp. 983-994. ISSN 0003-7028.

    Oliver, K.V. and Vilasi, A. and Marechal, Amandine and Moochhala, S.H. and Unwin, R.J. and Rich, P.R. (2016) Infrared vibrational spectroscopy: a rapid and novel diagnostic and monitoring tool for cystinuria. Scientific Reports (6), ISSN 2045-2322.

    Osborne, Andrew and Thalassinos, Kostas and Davies, Heledd (2016) Expansion of Lysine-rich repeats in Plasmodium proteins generates novel localisation sequences that target the periphery of the host Erythrocyte. Journal of Biological Chemistry 291 , pp. 26188-26207. ISSN 0021-9258.

    P

    Papaioannou, D. and Geibel, S. and Kunze, M.B.A. and Kay, C.W.M. and Waksman, Gabriel (2016) Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide. Protein Science 25 (3), pp. 627-637. ISSN 0961-8368.

    Penny, C.J. and Rahman, T. and Sula, A. and Miles, A.J. and Wallace, Bonnie A. and Patel, S. (2016) Isolated pores dissected from human two-pore channel 2 are functional. Scientific Reports 6 , p. 38426. ISSN 2045-2322.

    Pilorge, M. and Fassier, C. and Le Corronc, H. and Potey, A. and Bai, J. and De Gois, S. and Delaby, E. and Assouline, B. and Guinchat, V. and Devillard, F. and Delorme, R. and Nygren, G. and Råstam, M. and Meier, J.C. and Otani, S. and Cheval, H. and James, V.M. and Topf, Maya and Dear, T.N. and Gillberg, C. and Leboyer, M. and Giros, B. and Gautron, S. and Hazan, J. and Harvey, R.J. and Legendre, P. and Betancur, C. (2016) Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Molecular Psychiatry 21 , pp. 936-945. ISSN 1359-4184.

    Proietti, G and Abelak, K.K. and Bishop-Bailey, D. and Macchiarulo, A. and Nobeli, Irene (2016) Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2. Journal of Molecular Modeling 22 (11), p. 279. ISSN 1610-2940.

    R

    Rey, F.A. and Reguera, J. and Gerlach, P. and Rosenthal, M. and Gaudon, S. and Coscia, Francesca and Günther, S. and Cusack, S. (2016) Comparative structural and functional analysis of Bunyavirus and Arenavirus cap-snatching Endonucleases. PLOS Pathogens 12 (6), e1005636. ISSN 1553-7374.

    Ronzoni, R. and Berardelli, R. and Medicina, D. and Sitia, R. and Gooptu, Bibek and Fra, A.M. (2016) Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants. Human Molecular Genetics 25 (4), pp. 642-650. ISSN 0964-6906.

    S

    Santos, A.J.M. and Durkin, C.H. and Helaine, S. and Boucrot, Emmanuel and Holden, D.W. and McCormick, B.A. (2016) Clustered Intracellular Salmonella enterica Serovar Typhimurium blocks host cell cytokinesis. Infection and Immunity 84 (7), pp. 2149-2158. ISSN 0019-9567.

    Schuergers, N. and Lenn, T. and Kampmann, R. and Meissner, M.V. and Esteves, T. and Temerinac-Ott, M. and Korvink, J.G. and Lowe, Alan and Mullineaux, C.W. and Wilde, A. (2016) Cyanobacteria use micro-optics to sense light direction. eLife 5 , ISSN 2050-084X.

    Slingsby, Christine and Clark, A.R. (2016) The Family of Small Heat Shock Proteins: Assembly and Binding Functions. In: Gierasch, L.M. and Horwich, A.L. and Slingsby, Christine and Wickner, S. and Agard, D. (eds.) Structure and Action of Molecular Chaperones: Machines that Assist Protein Folding in the Cell. Series in Structural Biology 6. World Scientific, pp. 161-203. ISBN 9789814749329.

    Stubenrauch, C. and Belousoff, M.J. and Hay, I.D. and Shen, H.-H. and Lillington, James and Tuck, K.L. and Peters, K.M. and Phan, M.-D. and Lo, A.W. and Schembri, M.A. and Strugnell, R.A. and Waksman, Gabriel and Lithgow, T. (2016) Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine. Nature Microbiology 1 (7), p. 16064. ISSN 2058-5276.

    Sula, Altin and DeCaen, P. and Naylor, Claire and Zanatta, G. and Bagneris, Claire and Clapham, D.E. and Pryde, D. and Wallace, Bonnie A. (2016) Sodium Channel/Ligand complex structures as a guide for rational drug design. Biophysical Journal 110 (3), 33a. ISSN 0006-3495.

    T

    Terry, C. and Wenborn, A. and Gros, N. and Sells, J. and Joiner, S. and Hosszu, L.L.P. and Tattum, M.H. and Panico, Silvia and Clare, Daniel and Collinge, J. and Saibil, Helen R. and Wadsworth, J.D.F. (2016) Ex vivomammalian prions are formed of paired double helical prion protein fibrils. Open Biology 6 (5), p. 160035. ISSN 2046-2441.

    Thompson, Michael (2016) On matrix reference materials characterised by proficiency test. Analytical Methods 8 (24), pp. 4908-4911. ISSN 1759-9660.

    Thompson, Michael (2016) On the validation by inter-laboratory study of ‘procedures’ in chemical measurement. Analytical Methods 8 (46), pp. 8147-8150. ISSN 1759-9660.

    Thompson, Michael (2016) A careful look at traceability in chemical measurement. Analytical Methods 8 (5), pp. 940-941. ISSN 1759-9660.

    Thompson, Michael (2016) The comparison between reproducibility standard deviations from collaborative trials and proficiency tests: a preliminary study from food analysis. Analytical Methods 8 (4), pp. 742-746. ISSN 1759-9660.

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    Torres, L. and Kruger, A. and Csibra, E. and Gianni, E. and Pinheiro, Vitor B. (2016) Synthetic biology approaches to biological containment: pre-emptively tackling potential risks. Essays in Biochemistry 60 (4), pp. 393-410. ISSN 1744-1358.

    U

    Ukleja, Marta and Valpuesta, J.M. and Dziembowski, A. and Cuellar, J. (2016) Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms. BioEssays 38 (10), pp. 1048-1058. ISSN 0265-9247.

    V

    Valleix, S. and Verona, G. and Jourde-Chiche, N. and Nédelec, B. and Mangione, P.P. and Bridoux, F. and Mangé, A. and Dogan, A. and Goujon, J.-M. and Lhomme, M. and Dauteuille, C. and Chabert, M. and Porcari, R. and Waudby, Christopher and Relini, A. and Talmud, P.J. and Kovrov, O. and Olivecrona, G. and Stoppini, M. and CHRISTODOULOU, JOHN and Hawkins, P.N. and Grateau, G. and Delpech, M. and Kontush, A. and Gillmore, J.D. and Kalopissis, A.D. and Bellotti, V. (2016) D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile. Nature Communications 7 , p. 10353. ISSN 2041-1723.

    Vandavasi, V.G. and Langan, P.S. and Weiss, K.L. and Parks, J.M. and Cooper, Jonathan B. and Ginell, S.L. and Coates, L. (2016) Active-site protonation states in an Acyl-Enzyme intermediate of a Class A β-Lactamase with a Monobactam Substrate. Antimicrobial Agents and Chemotherapy 61 (1), e01636-16. ISSN 0066-4804.

    Vandavasi, V.G. and Weiss, K.L. and Cooper, Jonathan B. and Erskine, Peter T. and Tomanicek, S.J. and Ostermann, A. and Schrader, T.E. and Ginell, S.L. and Coates, L. (2016) Exploring the mechanism of β-Lactam Ring Protonation in the Class A β-lactamase Acylation Mechanism using neutron and X-ray crystallography. Journal of Medicinal Chemistry 59 (1), pp. 474-479. ISSN 0022-2623.

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    W

    Watermeyer, Jean M. and Hale, Victoria L. and Hackett, F. and Clare, Daniel K. and Cutts, E.E. and Vakonakis, I. and Fleck, R.A. and Blackman, M.J. and Saibil, Helen R. (2016) A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes. Blood 127 (3), pp. 343-351. ISSN 0006-4971.

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    Z

    Zeev-Ben-Mordehai, T. and Vasishtan, D. and Hernández Durán, A. and Vollmer, B. and White, P. and Prasad Pandurangan, A. and Siebert, C.A. and Topf, Maya and Grünewald, K. (2016) Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B. Proceedings of the National Academy of Sciences of the United States of America 113 (15), pp. 4176-4181. ISSN 0027-8424.

    This list was generated on Tue Nov 21 01:22:18 2017 GMT.