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    Synthesis of putative chain terminators of mycobacterial arabinan biosynthesis

    Smellie, I. and Bhakta, Sanjib and Sim, E. and Fairbanks, A. (2007) Synthesis of putative chain terminators of mycobacterial arabinan biosynthesis. Organic and Biomolecular Chemistry 5 (14), pp. 2257-2266. ISSN 1477-0520.

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    Abstract

    The synthesis of a variety of arabinose derivatives that have been modified at C-5 was achieved from D-arabinose. The 5-fluoro and 5-methoxy compounds were converted into the corresponding farnesyl phosphodiesters as putative chain terminators of mycobacterial arabinan biosynthesis. Biological testing of these materials revealed no effective anti-mycobacterial activity.

    Metadata

    Item Type: Article
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Depositing User: Sarah Hall
    Date Deposited: 30 Apr 2019 09:32
    Last Modified: 30 Apr 2019 09:32
    URI: http://eprints.bbk.ac.uk/id/eprint/27361

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