BIROn - Birkbeck Institutional Research Online

    New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer

    Gouge, Jerome and Vannini, A. (2017) New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer. Transcription 9 (1), pp. 61-66. ISSN 2154-1272.

    [img]
    Preview
    Text
    Gouge and Vannini - 2017 - New tricks for an old dog Brf2-dependent RNA Poly.pdf - Published Version of Record
    Available under License Creative Commons Attribution.

    Download (538kB) | Preview

    Abstract

    Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.

    Metadata

    Item Type: Article
    Keyword(s) / Subject(s): Brf2, Nrf2, redox stress, RNA polymerase III, transcription
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Divisions > Birkbeck Schools and Departments > School of Science > Biological Sciences
    Research Centres and Institutes: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Jerome Gouge
    Date Deposited: 04 Mar 2020 13:05
    Last Modified: 01 Jul 2020 19:29
    URI: http://eprints.bbk.ac.uk/id/eprint/31006

    Statistics

    Downloads
    Activity Overview
    84Downloads
    25Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item