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    ValiDichro: a website for validating and quality control of protein circular dichroism spectra

    Woollett, Benjamin and Whitmore, Lee and Janes, R.W. and Wallace, Bonnie A. (2013) ValiDichro: a website for validating and quality control of protein circular dichroism spectra. Nucleic Acids Research 41 (W1), W417-W421. ISSN 0305-1048.

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    Abstract

    Circular dichroism (CD) spectroscopy is widely used in structural biology as a technique for examining the structure, folding and conformational changes of proteins. A new server, ValiDichro, has been developed for checking the quality and validity of CD spectral data and metadata, both as an aid to data collection and processing and as a validation procedure for spectra to be included in publications. ValiDichro currently includes 25 tests for data completeness, consistency and quality. For each test that is done, not only is a validation report produced, but the user is also provided with suggestions for correcting or improving the data. The ValiDichro server is freely available at http://valispec.cryst.bbk.ac.uk/circularDichroism/ValiDichro/upload.html.

    Metadata

    Item Type: Article
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Research Centre: Bioinformatics, Bloomsbury Centre for, Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 01 May 2013 07:37
    Last Modified: 28 Jul 2019 04:02
    URI: http://eprints.bbk.ac.uk/id/eprint/6541

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