Experimental approaches for gene regulatory network construction: the chick as a model system
Streit, A. and Tambalo, M. and Chen, J. and Grocott, T. and Anwar, M. and Sosinsky, Alona and Stern, C.D. (2013) Experimental approaches for gene regulatory network construction: the chick as a model system. Genesis 51 (5), pp. 296-310. ISSN 1526-954X.
Abstract
Setting up the body plan during embryonic development requires the coordinated action of many signals and transcriptional regulators in a precise temporal sequence and spatial pattern. The last decades have seen an explosion of information describing the molecular control of many developmental processes. The next challenge is to integrate this information into logic “wiring diagrams” that visualize gene actions and outputs, have predictive power and point to key control nodes. Here, we provide an experimental workflow on how to construct gene regulatory networks using the chick as model system. genesis 51:296–310, 2012.
Metadata
| Item Type: | Article |
|---|---|
| Keyword(s) / Subject(s): | transcription factors, transcriptome analysis, conserved regulatory elements |
| School: | Birkbeck Schools and Departments > School of Science > Biological Sciences |
| Depositing User: | Administrator |
| Date Deposited: | 07 Jun 2013 12:59 |
| Last Modified: | 11 Oct 2016 11:58 |
| URI: | http://eprints.bbk.ac.uk/id/eprint/7393 |
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