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Experimental approaches for gene regulatory network construction: the chick as a model system

Streit, A. and Tambalo, M. and Chen, J. and Grocott, T. and Anwar, M. and Sosinsky, Alona and Stern, C.D. (2013) Experimental approaches for gene regulatory network construction: the chick as a model system. Genesis 51 (5), pp. 296-310. ISSN 1526-954X.

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Abstract

Setting up the body plan during embryonic development requires the coordinated action of many signals and transcriptional regulators in a precise temporal sequence and spatial pattern. The last decades have seen an explosion of information describing the molecular control of many developmental processes. The next challenge is to integrate this information into logic “wiring diagrams” that visualize gene actions and outputs, have predictive power and point to key control nodes. Here, we provide an experimental workflow on how to construct gene regulatory networks using the chick as model system. genesis 51:296–310, 2012.

Metadata

Item Type: Article
Keyword(s) / Subject(s): transcription factors, transcriptome analysis, conserved regulatory elements
School: Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
Depositing User: Administrator
Date Deposited: 07 Jun 2013 12:59
Last Modified: 02 Aug 2023 17:05
URI: https://eprints.bbk.ac.uk/id/eprint/7393

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