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    Genome gating in tailed bacteriophage capsids

    Tavares, P. and Zinn-Justin, S. and Orlova, Elena (2011) Genome gating in tailed bacteriophage capsids. In: Rossmann, M.G. and Rao, V.B. (eds.) Viral Molecular Machines. Advances in Experimental Medicine and Biology 726 726. New York, U.S.: Springer, pp. 585-600. ISBN 9781461409809.

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    Abstract

    Written by leaders in their respective fields Uses the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance Conveys state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics A biological organism can be viewed as a collection of molecular machines well integrated to function as a self-replicating unit. One of the principal goals in biology is to be able to fully understand the mechanisms of an organism in atomic detail. Viruses offer the best opportunities to achieve this goal. Written by leaders in the respective fields, this book examines a variety of viral molecular machines, using the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, assembly of structural components, genome packaging and maturation into an infectious virion. The book conveys the state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics. Viral Molecular Machines is not only a “must-have” book for virologists but it will also be broadly useful for molecular biologists in academia and industry as well as an educational tool for teaching graduate and upper level undergraduate students.

    Metadata

    Item Type: Book Section
    School: Birkbeck Schools and Departments > School of Science > Biological Sciences
    Research Centre: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Sarah Hall
    Date Deposited: 29 Jan 2014 16:59
    Last Modified: 06 Dec 2016 11:14
    URI: http://eprints.bbk.ac.uk/id/eprint/9132

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