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    Microstructural differences in the thalamus and thalamic radiations in the congenitally deaf

    Rebecca Lyness, C. and Alvarez, I. and Sereno, Martin I. and MacSweeney, M. (2014) Microstructural differences in the thalamus and thalamic radiations in the congenitally deaf. NeuroImage 100 , pp. 347-357. ISSN 1053-8119.

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    Abstract

    There is evidence of both crossmodal and intermodal plasticity in the deaf brain. Here, we investigated whether sub-cortical plasticity, specifically of the thalamus, contributed to this reorganisation. We contrasted diffusion weighted magnetic resonance imaging data from 13 congenitally deaf and 13 hearing participants, all of whom had learnt British Sign Language after 10 years of age. Connectivity based segmentation of the thalamus revealed changes to mean and radial diffusivity in occipital and frontal regions, which may be linked to enhanced peripheral visual acuity, and differences in how visual attention is deployed in the deaf group. Using probabilistic tractography, tracts were traced between the thalamus and its cortical targets, and microstructural measurements were extracted from these tracts. Group differences were found in microstructural measurements of occipital, frontal, somatosensory, motor and parietal thalamo-cortical tracts. Our findings suggest there is sub-cortical plasticity in the deaf brain, and that white matter alterations can be found throughout the deaf brain, rather than being restricted to, or focussed in auditory cortex.

    Metadata

    Item Type: Article
    Keyword(s) / Subject(s): Diffusion Weighted MRI, Deafness, Thalamus, Neuroplasticity
    School: Birkbeck Schools and Departments > School of Science > Psychological Sciences
    Depositing User: Administrator
    Date Deposited: 06 Jun 2014 14:41
    Last Modified: 04 Aug 2019 04:54
    URI: http://eprints.bbk.ac.uk/id/eprint/9876

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