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    Architectures and biogenesis of non-flagellar protein appendages in gram-negative bacteria

    Fronzes, Remi and Remaut, Han and Waksman, Gabriel (2008) Architectures and biogenesis of non-flagellar protein appendages in gram-negative bacteria. Embo Journal 27 (17), pp. 2271-2280. ISSN 0261-4189.

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    Bacteria commonly expose non-flagellar proteinaceous appendages on their outer surfaces. These extracellular structures, called pili or fimbriae, are employed in attachment and invasion, biofilm formation, cell motility or protein and DNA transport across membranes. Over the past 15 years, the power of molecular and structural techniques has revolutionalized our understanding of the biogenesis, structure, function and mode of action of these bacterial organelles. Here, we review the five known classes of Gram-negative non-flagellar appendages from a biosynthetic and structural point of view.


    Item Type: Article
    Keyword(s) / Subject(s): bacterial pathogenesis, fimbriae, pilus, secretion system
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
    Research Centres and Institutes: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 04 Aug 2010 14:09
    Last Modified: 02 Aug 2023 16:49


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