BIROn - Birkbeck Institutional Research Online

    The Protein Circular Dichroism Data Bank (PCDDB) - first release of a new resource for spectroscopic data sharing

    Whitmore, Lee and Woollett, Benjamin and Miles, Andrew J. and Janes, R.W. and Wallace, Bonnie A. (2010) The Protein Circular Dichroism Data Bank (PCDDB) - first release of a new resource for spectroscopic data sharing. Biophysical Journal 98 (3(S1)), 196a-197a. ISSN 0006-3495.

    Full text not available from this repository.


    The Protein Circular Dichroism Data Bank (PCDDB) has been designed as a resource for the deposition of circular dichroism (CD) spectroscopic data and accompanying meta-data, with links to sequence and structure data bases and citation references. A key aim of the PCDDB is to provide a repository for spectroscopic data in a comparable manner to that of the long-established Protein Data Bank (PDB), which contains three-dimensional structures of proteins and their associated crystallographic, NMR or cryo-EM data. The PCDDB will be a searchable data bank of CD spectra, with associated tools and protocols for spectral matching, analysis and back-calculations available as part of the overall resource. In addition, validation software will be available for verification of the quality of the CD data deposited, in order to maintain a high standard of data incorporated into this resource. The PCDDB will accommodate both conventional (lab-based) CD data and synchrotron radiation circular dichroism (SRCD) data. It will provide for easy wide-spread dissemination of research results and a facility for data sharing, as a simple means of fulfilling granting body requirements. The first release of the Protein Circular Dichroism Data Bank was made publicly-available in September 2009. The first entries were of the 71 proteins that comprise the SP175 reference database (Lees et al., Bioinformatics 22:1955; 2006). In the current release, users can download and access these data files. In the full beta release, due in late 2009/early 2010, users will be able to deposit their own spectra, which will be validated before being made openly available on line. The PCDDB can be accessed through the website


    Item Type: Article
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
    Research Centres and Institutes: Bioinformatics, Bloomsbury Centre for (Closed), Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 04 Aug 2010 14:09
    Last Modified: 02 Aug 2023 16:49


    Activity Overview
    6 month trend
    6 month trend

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item