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    Optical imaging of brain activation in Gambian infants

    Papademetriou, M. and Lloyd-Fox, Sarah and Everdell, N.L. and Darboe, M.K. and Moore, S.E. and Prentice, A.M. and Elwell, Clare (2014) Optical imaging of brain activation in Gambian infants. In: Swartz, H.M. and Harrison, D.K. and Bruley, D.F. (eds.) Oxygen Transport to Tissue XXXVI. Advances in Experimental Medicine and Biology 812 812. New York, U.S.: Springer, pp. 263-269. ISBN 9781493905836.

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    We used optical topography (OT) to investigate cognitive function in infants in rural Gambia. Images of changes in oxyhaemoglobin and deoxyhaemoglobin concentrations were reconstructed using a multispectral algorithm which uses the finite element method (FEM) to model the propagation of light through scattering tissue using the diffusion equation. High quality OT data enabled us to reconstruct images with robust representation of haemodynamic changes. OT is a feasible neuroimage technology for this resource-poor setting.


    Item Type: Book Section
    Keyword(s) / Subject(s): Brain development, Infant undernutrition, Functional near infrared spectroscopy
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Psychological Sciences
    Research Centres and Institutes: Brain and Cognitive Development, Centre for (CBCD)
    Depositing User: Administrator
    Date Deposited: 11 May 2015 10:21
    Last Modified: 02 Aug 2023 17:16


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