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    Does attention constrain developmental trajectories in fragile X syndrome? a 3-year longitudinal study

    Cornish, K. and Cole, V. and Longhi, E. and Karmiloff-Smith, Annette and Scerif, G. (2012) Does attention constrain developmental trajectories in fragile X syndrome? a 3-year longitudinal study. American Journal on Intellectual and Developmental Disabilities 117 (2), pp. 103-120. ISSN 1944-7558.

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    Basic attentional processes and their impact on developmental trajectories in fragile X syndrome were assessed in a 3-year prospective study. Although fragile X syndrome is a monogenic X-linked disorder, there is striking variability in outcomes even in young boys with the condition. Attention is a key factor constraining interactions with the environment, so it is a perfect candidate to predict trajectories in cognitive and behavioral outcomes. In this study, 48 boys with fragile X syndrome were assessed 3 times over 24 months. Although nonverbal IQ declined, there were significant improvements in nonverbal growth scores and in cognitive attention. In contrast, behavioral difficulties (i.e., autistic symptomatology, hyperactivity–inattention) remained stable over this time frame. Attentional markers in the visual and auditory modalities predicted intellectual abilities and classroom behavior, whereas auditory markers alone predicted autistic symptomatology.


    Item Type: Article
    Keyword(s) / Subject(s): fragile X syndrome, attention, developmental trajectories, longitudinal
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Psychological Sciences
    Research Centres and Institutes: Brain and Cognitive Development, Centre for (CBCD)
    Depositing User: Sarah Hall
    Date Deposited: 17 Sep 2015 10:56
    Last Modified: 02 Aug 2023 17:18


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