Synthesis of putative chain terminators of mycobacterial arabinan biosynthesis

Smellie, I. and Bhakta, Sanjib and Sim, E. and Fairbanks, A. (2007) Synthesis of putative chain terminators of mycobacterial arabinan biosynthesis. Organic and Biomolecular Chemistry 5 (14), pp. 2257-2266. ISSN 1477-0520.

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Official URL: http://dx.doi.org/10.1039/B704788F

Abstract

The synthesis of a variety of arabinose derivatives that have been modified at C-5 was achieved from D-arabinose. The 5-fluoro and 5-methoxy compounds were converted into the corresponding farnesyl phosphodiesters as putative chain terminators of mycobacterial arabinan biosynthesis. Biological testing of these materials revealed no effective anti-mycobacterial activity.

Metadata

Item Type:	Article
School:	Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
Depositing User:	Sarah Hall
Date Deposited:	30 Apr 2019 09:32
Last Modified:	02 Aug 2023 17:51
URI:	https://eprints.bbk.ac.uk/id/eprint/27361

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