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    Language-impaired children: no sign of the FOXP2 mutation

    Meaburn, Emma and Dale, P.S. and Craig, I.W. and Plomin, R. (2002) Language-impaired children: no sign of the FOXP2 mutation. NeuroReport 13 (8), pp. 1075-1077. ISSN 0959-4965.

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    Abstract

    A mutation in the FOXP2 gene has been found to be responsible for the autosomal dominant inheritance of a severe form of speech and language impairment in a family known as KE. We genotyped the FOXP2 mutation for 270 4-year-old children selected for low general language scores from a representative community sample of more than 18,000 children. No language-impaired child had the FOXP2 mutation. Although rare severe disorders such as those of the KE family are often caused by a single gene, common disorders such as language impairment are more likely to be the quantitative extreme of the same multiple genetic factors responsible for heritability throughout the distribution.

    Metadata

    Item Type: Article
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Psychological Sciences
    Depositing User: Sarah Hall
    Date Deposited: 07 Jan 2020 13:12
    Last Modified: 02 Aug 2023 17:56
    URI: https://eprints.bbk.ac.uk/id/eprint/30517

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