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    Language-impaired children: no sign of the FOXP2 mutation

    Meaburn, Emma and Dale, P.S. and Craig, I.W. and Plomin, R. (2002) Language-impaired children: no sign of the FOXP2 mutation. NeuroReport 13 (8), pp. 1075-1077. ISSN 0959-4965.

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    A mutation in the FOXP2 gene has been found to be responsible for the autosomal dominant inheritance of a severe form of speech and language impairment in a family known as KE. We genotyped the FOXP2 mutation for 270 4-year-old children selected for low general language scores from a representative community sample of more than 18,000 children. No language-impaired child had the FOXP2 mutation. Although rare severe disorders such as those of the KE family are often caused by a single gene, common disorders such as language impairment are more likely to be the quantitative extreme of the same multiple genetic factors responsible for heritability throughout the distribution.


    Item Type: Article
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Psychological Sciences
    Depositing User: Sarah Hall
    Date Deposited: 07 Jan 2020 13:12
    Last Modified: 02 Aug 2023 17:56


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