BIROn - Birkbeck Institutional Research Online

    Tools and methods for Circular Dichroism Spectroscopy of proteins

    Miles, Andrew and Janes, R.W. and Wallace, Bonnie A. (2021) Tools and methods for Circular Dichroism Spectroscopy of proteins. Chemical Society Reviews , ISSN 0306-0012. (In Press)

    [img]
    Preview
    Text
    43986.pdf - Published Version of Record
    Available under License Creative Commons Attribution Non-commercial.

    Download (3MB) | Preview

    Abstract

    Circular dichroism (CD) spectroscopy is a widely-used method in biochemistry, structural biology and pharmaceutical chemistry. More than 24 000 papers published in the past decade have included CD characterisations of proteins; many of those studies have also included other complementary chemical, biophysical, and computational chemistry methods. This tutorial review describes the background to the technique of CD spectroscopy and good practice methods for high quality data collection. It specifically focuses on both established and new methods and tools available for experimental design and interpretation, data processing, visualisation, analysis, validation, archiving, and accession, including tools developed to enhance the complementarity of this method with other structural and chemical biology studies.

    Metadata

    Item Type: Article
    School: School of Science > Biological Sciences
    Depositing User: Administrator
    Date Deposited: 23 Apr 2021 12:39
    Last Modified: 08 Jul 2021 02:16
    URI: https://eprints.bbk.ac.uk/id/eprint/43986

    Statistics

    Downloads
    Activity Overview
    6Downloads
    11Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item