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    Feedforward somatosensory inhibition is normal in cervical dystonia

    Ferrè, Elisa Raffaella and Ganos, C. and Bhatia, K. and Haggard, P. (2015) Feedforward somatosensory inhibition is normal in cervical dystonia. Parkinsonism & Related Disorders 21 (3), pp. 266-270. ISSN 1353-8020.

    Ferre_PARKINSONISM_RELATED_DISORDERS_2015.pdf - Author's Accepted Manuscript

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    Background: Insufficient cortical inhibition is a key pathophysiological finding in dystonia. Subliminal sensory stimuli were reported to transiently inhibit somatosensory processing. Here we investigated whether such subliminal feedforward inhibition is reduced in patients with cervical dystonia. Methods: Sixteen cervical dystonia patients and 16 matched healthy controls performed a somatosensory detection task. We measured the drop in sensitivity to detect a threshold-level digital nerve shock when it was preceded by a subliminal conditioning shock, compared to when it was not. Results: Subliminal conditioning shocks reduced sensitivity to threshold stimuli to a similar extent in both patients and controls, suggesting that somatosensory subliminal feedforward inhibition is normal in cervical dystonia. Conclusion: Somatosensory feedforward inhibition was normal in this group of cervical dystonia patients. Our results qualify previous concepts of a general dystonic deficit in sensorimotor inhibitory processing.


    Item Type: Article
    Keyword(s) / Subject(s): Cervical dystonia, Subliminal feed, forward inhibition, Cortical inhibition
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Psychological Sciences
    Depositing User: Elisa Raffaella Ferre
    Date Deposited: 29 Sep 2021 09:48
    Last Modified: 02 Aug 2023 18:12


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