Cryo-EM in molecular and cellular biology

Saibil, Helen (2022) Cryo-EM in molecular and cellular biology. Molecular Cell 82 (2), pp. 274-284. ISSN 1097-2765.

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Official URL: https://doi.org/10.1016/j.molcel.2021.12.016

Abstract

This review summarizes the current state of methods and results achievable by cryo-electron microscopy (cryo-EM) imaging for molecular, cell, and structural biologists who wish to understand what is required and how it might help to address their research questions. It covers some of the main issues in sample preparation, microscopes and data collection, image processing, three-dimensional (3D) reconstruction, and validation and interpretation of the resulting EM density maps and atomic models. [Abstract copyright: Copyright © 2021 Elsevier Inc. All rights reserved.]

Metadata

Item Type:	Article
School:	Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
SWORD Depositor:	Mr Joe Tenant
Depositing User:	Mr Joe Tenant
Date Deposited:	19 Jul 2022 09:10
Last Modified:	02 Aug 2023 18:15
URI:	https://eprints.bbk.ac.uk/id/eprint/47469

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