BIROn - Birkbeck Institutional Research Online

    Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity

    Hemming, Joanna M. and Szyroka, Justyna and Shokano, Gracia and Arnold, T. and Skoda, M.W.A. and Rennie, A.R. and Thompson, Katherine C. (2022) Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity. Environmental Science: Atmospheres 2022 (2), pp. 753-760. ISSN 2634-3606.

    [img]
    Preview
    Text
    48587a.pdf - Published Version of Record
    Available under License Creative Commons Attribution.

    Download (700kB) | Preview

    Abstract

    Exposure to the secondary pollutant ozone in ambient air is associated with adverse health effects when inhaled. In this work we use surface pressure measurements, combined with X-ray and neutron reflection, to observe changes in a layer of lung surfactant at the air water interface when exposed to gas phase ozone. The results demonstrate that the layer reacts with ozone changing its physical characteristics. A slight loss of material, a significant thinning of the layer and increased hydration of the surfactant material is observed. The results support the hypothesis that unsaturated lipids present in lung surfactant are still susceptible to rapid reaction with ozone and the reaction changes the properties of the interfacial layer.

    Statistics

    Activity Overview
    6 month trend
    0Downloads
    6 month trend
    0Hits

    Additional statistics are available via IRStats2.

    Archive Staff Only (login required)

    Edit/View Item Edit/View Item