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    Article

    Grey, W. and Chauhan, R. and Piganeau, M. and Huerga, E. and Garcia-Albornoz, M. and McDonald, Neil and Bonnet, D. (2020) Activation of the Receptor Tyrosine Kinase, RET, improves long-term Hematopoietic Stem Cell outgrowth and potency. Blood , ISSN 0006-4971. (In Press)

    Moccia, M. and Frett, B. and Zhang, L. and Lakkaniga, R. and Briggs, D.C. and Chauhan, R. and Brescia, A. and Federico, G. and Santoro, M. and McDonald, Neil Q. and Li, H. and Carlomagno, F. (2020) Bioisosteric discovery of NPA101.3, a second generation RET/VEGFR2 inhibitor optimized for single-agent polypharmacology. Journal of Medicinal Chemistry 63 (9), pp. 4506-4516. ISSN 0022-2623.

    Nakaoku, T. and Kohno, T. and Araki, M. and Niho, S. and Chauhan, R. and Knowles, P.P. and Tsuchihara, K. and Matsumoto, S. and Shimada, Y. and Mimaki, S. and Ishii, G. and Ichikawa, H. and Nagatoishi, S. and Tsumoto, K. and Okuno, Y. and Yoh, K. and McDonald, Neil Q. and Goto, K. (2018) A secondary RET mutation in the activation loop conferring resistance to vandetanib. Nature Communications 9 (1), p. 625. ISSN 2041-1723.

    Plenker, D. and Riedel, M. and Brägelmann, J. and Dammert, M.A. and Chauhan, R. and Knowles, P.P. and Lorenz, C. and Keul, M. and Bührmann, M. and Pagel, O. and Tischler, V. and Scheel, A.H. and Schütte, D. and Song, Y. and Stark, J. and Mrugalla, F. and Alber, Y. and Richters, A. and Engel, J. and Leenders, F. and Heuckmann, J.M. and Wolf, J. and Diebold, J. and Pall, G. and Peifer, M. and Aerts, M. and Gevaert, K. and Zahedi, R.P. and Buettner, R. and Shokat, K.M. and McDonald, Neil Q. and Kast, S.M. and Gautschi, O. and Thomas, R.K. and Sos, M.L. (2017) Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Science Translational Medicine 9 (394), ISSN 1946-6234.

    Plenker, D. and Riedel, M. and Brägelmann, J. and Dammert, M.A. and Chauhan, R. and Knowles, P.K. and Lorenz, C. and Keul, M. and Bührmann, M. and Pagel, O. and Tischler, V. and Scheel, A.H. and Schütte, D. and Song, Y. and Stark, J. and Mrugalla, F. and Alber, Y. and Richters, A. and Engel, J. and Leenders, F. and Heuckmann, J.M. and Wolf, J. and Diebold, J. and Pall, G. and Peifer, M. and Aerts, M. and Gevaert, K. and Zahedi, R.P. and Buettner, R. and Shokat, K.M. and McDonald, Neil Q. and Kast, S.M. and Gautschi, O. and Thomas, R.K. and Sos, M.L. (2017) Mechanistic insight into RET kinase inhibitors targeting the DFG-out conformation in RET-rearranged cancer. Science Translational Medicine 9 (394), ISSN 1946-6234.

    This list was generated on Mon Dec 6 15:29:24 2021 GMT.