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April 2008
Baldwin, A.J. and Anthony-Cahill, S.J. and Knowles, T.P.J. and Lippens, G. and Christodoulou, John and Barker, P.D. and Dobson, C.M. (2008) Measurement of amyloid fibril length distributions by inclusion of rotational motion in solution NMR diffusion measurements. Angewandte Chemie - International Edition 47 (18), pp. 3385-3387. ISSN 1433-7851.
May 2008
Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2008) Molecular determinants of the aggregation behavior of alpha- and beta-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.
Gsponer, J. and Christodoulou, John and Cavalli, A. and Bui, J.M. and Richter, B. and Dobson, C.M. and Vendruscolo, M. (2008) A coupled equilibrium shift mechanism in Calmodulin-Mediated signal transduction. Structure 16 (5), pp. 736-746. ISSN 0969-2126.
October 2008
Roodveldt, C. and Bertoncini, C.W. and Andersson, A. and van der Goot, A.T. and Hsu, S.T.D. and Fernandez Montesinos, R. and de Jong, J. and van Ham, T.J. and Nollen, E.A. and Pozo, D. and Christodoulou, John and Dobson, C.M. (2008) Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip. Embo Journal 28 (23), pp. 3758-3770. ISSN 0261-4189.
Chan, P.H. and Pardon, E. and Menzer, L. and de Genst, E. and Kumita, J.R. and Christodoulou, John and Saerens, D. and Brans, A. and Bouillenne, F. and Archer, D.B. and Robinson, C.V. and Muyldermans, S. and Matagne, A. and Redfield, C. and Wyns, L. and Dobson, C.M. and Demoulin, M. (2008) Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils. Biochemistry 47 (42), pp. 11041-11054. ISSN 0006-2960.
Roodveldt, C. and Christodoulou, John and Dobson, C.M. (2008) Immunological features of alpha-synuclein in Parkinson's disease. Journal of Cellular and Molecular Medicine 12 (5B), pp. 1820-1829. ISSN 1582-1838.
2009
Christodoulou, John and Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Dobson, C.M. (2009) Probing protein folding on the Ribosome by Solution State NMR Spectroscopy. Journal of Biomolecular Structure & Dynamics 26 (6), p. 94. ISSN 0739-1102.
May 2009
Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2009) Molecular determinants of the aggregation behavior of α- and β-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.
Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Dobson, C.M. and Christodoulou, John (2009) Structure, dynamics and folding of an Immunoglobulin Domain of the Gelation Factor (ABP-120) from Dictyostelium discoideum. Journal of Molecular Biology 388 (4), pp. 865-879. ISSN 0022-2836.
June 2009
Hsu, S.T.D. and Cabrita, L.D. and Christodoulou, John and Dobson, C.M. (2009) H-1, N-15 and C-13 assignments of domain 5 of Dictyostelium discoideum gelation factor (ABP-120) in its native and 8M urea-denatured states. Biomolecular Nmr Assignments 3 (1), pp. 29-31. ISSN 1874-2718.
Hsu, S.T.D. and Cabrita, L.D. and Fucini, P. and Christodoulou, John and Dobson, C.M. (2009) Probing side-chain dynamics of a ribosome-bound nascent chain using methyl NMR spectroscopy. Journal of the American Chemical Society 131 (24), pp. 8366-8367. ISSN 0002-7863.
September 2009
Lendel, C. and Bertoncini, C.W. and Cremades, N. and Waudby, Christopher A. and Vendruscolo, M. and Dobson, C.M. and Schenk, D. and Christodoulou, John and Toth, G. (2009) On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with congo red and lacmoid. Biochemistry 48 (35), pp. 8322-8334. ISSN 0006-2960.
December 2009
Vuchelen, A. and O’Day, E. and de Genst, E. and Pardon, E. and Lode Wyns, L. and Dobson, C.M. and Christodoulou, John and Hsu, S.T.D. (2009) 1H, 13C and 15N assignments of a camelid nanobody directed against human α-synuclein. Biomolecular Nmr Assignments 3 (2), pp. 231-233. ISSN 1874-2718.
Cabrita, L.D. and Hsu, S.T.D. and Launay, H. and Dobson, C.M. and Christodoulou, John (2009) Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America 106 (52), pp. 22239-22244. ISSN 0027-8424.
2010
O’Brien, E.P. and Hsu, S.T.D. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2010) Transient tertiary structure formation within the Ribosome Exit Port. Journal of the American Chemical Society 132 (47), pp. 16928-16937. ISSN 0002-7863.
February 2010
Cabrita, L.D. and Dobson, C.M. and Christodoulou, John (2010) Protein folding on the ribosome. Current Opinion in Structural Biology 20 (1), pp. 33-45. ISSN 0959-440X.
June 2010
Cabrita, L.D. and Dobson, C.M. and Christodoulou, John (2010) Early nascent chain folding events on the ribosome. Israel Journal of Chemistry 50 (1), pp. 99-108. ISSN 0021-2148.
2011
O’Brien, E.P. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2011) New scenarios of protein folding can occur on the Ribosome. Journal of the American Chemical Society 133 (3), pp. 513-526. ISSN 0002-7863.
2012
Waudby, Christopher A. and Mantle, M.D. and Cabrita, L.D. and Gladden, L.F. and Dobson, C.M. and Christodoulou, John (2012) Rapid Distinction of Intracellular and Extracellular Proteins Using NMR Diffusion Measurements. Journal of the American Chemical Society 134 (28), pp. 11312-11315. ISSN 0002-7863.
7 March 2012
O’Brien, E.P. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2012) Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant Cytosolic interactions. Journal of the American Chemical Society 134 (26), pp. 10920-10932. ISSN 0002-7863.
2013
Temussi, P.A. and Waudby, Christopher A. and Camilloni, C. and Fitzpatrick, A.W.P. and Cabrita, L.D. and Dobson, C.M. and Vendruscolo, M. and Christodoulou, John (2013) In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-Synuclein within E. coli cells. PLoS One 8 (8), e72286. ISSN 1932-6203.
April 2016
Cabrita, Lisa D. and Cassaignau, Anaïs M.E. and Launay, Hélène M.M. and Waudby, Christopher A. and Wlodarski, Tomasz and Camilloni, C. and Karyadi, Maria-Evangelia and Robertson, Amy L. and Wang, Xiaolin and Wentink, Anne S. and Goodsell, Luke S. and Woolhead, C.A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2016) A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding. Nature Structural & Molecular Biology 23 (4), pp. 278-285. ISSN 1545-9993.
3 May 2016
Deckert, Annika and Waudby, Christopher and Wlodarski, Tomasz and Wentink, Anne and Wang, Xiaolin and Kirkpatrick, John and Paton, Jack and Camilloni, C. and Kukic, P. and Dobson, C.M. and Vendruscolo, M. and Cabrita, Lisa and Christodoulou, John (2016) Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor. Proceedings of the National Academy of Sciences of the United States of America 113 (18), pp. 5012-5017. ISSN 0027-8424.
6 December 2016
Ahn, M. and Hagan, C.L. and Bernardo-Gancedo, A. and De Genst, E. and Newby, F.N. and Christodoulou, John and Dhulesia, A. and Dumoulin, M. and Robinson, C.V. and Dobson, C.M. and Kumita, J.R. (2016) The significance of the location of mutations for the native-state dynamics of human Lysozyme. Biophysical Journal 111 (11), pp. 2358-2367. ISSN 0006-3495.
3 November 2017
Ahn, M. and Waudby, C.A. and Bernardo-Gancedo, A. and De Genst, E. and Dhulesia, A. and Salvatella, X. and Christodoulou, John and Dobson, C.M. and Kumita, J.R. (2017) Application of Lysine-specific labeling to detect transient interactions present during human Lysozyme Amyloid Fibril formation. Scientific Reports 7 (1), ISSN 2045-2322.
10 July 2019
Waudby, Christopher A. and Dobson, C.M. and Christodoulou, John (2019) Nature and regulation of protein folding on the ribosome. Trends in Biochemical Sciences , ISSN 0968-0004.
19 September 2019
Wang, X. and Kirkpatrick, J.P. and Launay, H.M.M and de Simone, A. and Häussinger, D. and Dobson, C.M. and Vendruscolo, M. and Cabrita, L.D. and Waudby, C.A. and Christodoulou, John (2019) Probing the dynamic stalk region of the ribosome using solution NMR. Scientific Reports 9 (1), p. 13528. ISSN 2045-2322.