BIROn - Birkbeck Institutional Research Online
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    Number of items: 8.

    March 2008

    Roces, L. and Knowles, P.P. and Fox, G. and Juanhuix, J. and Scaplehorn, N. and Way, M. and McDonald, Neil Q. (2008) Crystallization and preliminary X-ray diffraction analysis of vaccinia virus H1L phosphatase. Acta Crystallographica Section F F64 (3), pp. 190-192. ISSN 1744-3091.

    August 2008

    Kirk, R. and Laman, H. and Knowles, P.P. and Murray-Rust, J. and Lomonosov, M. and Meziane, E.K. and McDonald, Neil Q. (2008) Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor. Journal of Biological Chemistry 283 (32), pp. 22325-22335. ISSN 0021-9258.

    February 2010

    Mologni, L. and Rostagno, R. and Brussolo, S. and Knowles, P.P. and Kjaer, S. and Murray-Rust, J. and Rosso, E. and Zambon, A. and Scapozza, L. and McDonald, Neil Q. and Lucchini, V. and Gambacorti-Passerini, C. (2010) Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors. Bioorganic & Medicinal Chemistry 18 (4), pp. 1482-1496. ISSN 1464-3391.

    1 April 2011

    Boëda, B. and Knowles, P.P. and Briggs, David C. and Murray-Rust, J. and Soriano, E. and Garvalov, B.K. and McDonald, Neil Q. and Way, M. (2011) Molecular recognition of the tes LIM2–3 domains by the actin-related protein arp7A. Journal of Biological Chemistry 286 (13), pp. 11543-11554. ISSN 0021-9258.

    6 March 2014

    Plaza-Menacho, I. and Barnouin, K. and Goodman, K. and Martínez-Torres, R.J. and Borg, A. and Murray-Rust, J. and Mouilleron, S. and Knowles, P.P. and McDonald, Neil Q. (2014) Oncogenic RET Kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans. Molecular Cell 53 (5), pp. 738-751. ISSN 1097-2765.

    September 2014

    Goodman, K.M. and Kjær, S. and Beuron, F. and Knowles, P.P. and Nawrotek, A. and Burns, E.M. and Purkiss, A.G. and George, R. and Santoro, M. and Morris, E.P. and McDonald, Neil Q. (2014) RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association. Cell Reports 18 (6), pp. 1894-1904. ISSN 2211-1247.

    14 June 2017

    Plenker, D. and Riedel, M. and Brägelmann, J. and Dammert, M.A. and Chauhan, R. and Knowles, P.P. and Lorenz, C. and Keul, M. and Bührmann, M. and Pagel, O. and Tischler, V. and Scheel, A.H. and Schütte, D. and Song, Y. and Stark, J. and Mrugalla, F. and Alber, Y. and Richters, A. and Engel, J. and Leenders, F. and Heuckmann, J.M. and Wolf, J. and Diebold, J. and Pall, G. and Peifer, M. and Aerts, M. and Gevaert, K. and Zahedi, R.P. and Buettner, R. and Shokat, K.M. and McDonald, Neil Q. and Kast, S.M. and Gautschi, O. and Thomas, R.K. and Sos, M.L. (2017) Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Science Translational Medicine 9 (394), ISSN 1946-6234.

    12 February 2018

    Nakaoku, T. and Kohno, T. and Araki, M. and Niho, S. and Chauhan, R. and Knowles, P.P. and Tsuchihara, K. and Matsumoto, S. and Shimada, Y. and Mimaki, S. and Ishii, G. and Ichikawa, H. and Nagatoishi, S. and Tsumoto, K. and Okuno, Y. and Yoh, K. and McDonald, Neil Q. and Goto, K. (2018) A secondary RET mutation in the activation loop conferring resistance to vandetanib. Nature Communications 9 (1), p. 625. ISSN 2041-1723.

    This list was generated on Mon Nov 18 04:16:48 2019 GMT.