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    Article

    Brennan, A.J. and Law, R.H.P. and Conroy, P.J. and Noori, T. and Lukoyanova, Natalya and Saibil, Helen R. and Yagita, H. and Ciccone, A. and Verschoor, S. and Whisstock, J.C. and Trapani, J.A. and Voskoboinik, I. (2018) Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death & Differentiation , ISSN 1350-9047. (In Press)

    Dudkina, Natalya and Spicer, B.A. and Reboul, C.F. and Conroy, P.J. and Lukoyanova, Natalya and Elmlund, H. and Law, R.H.P. and Ekkel, S.M. and Kondos, S.C. and Goode, R.J.A. and Ramm, G. and Whisstock, J.C. and Saibil, Helen R. and Dunstone, M.A. (2016) Structure of the poly-C9 component of the complement membrane attack complex. Nature Communications 7 , p. 10588. ISSN 2041-1723.

    Lukoyanova, Natalya and Kondos, S.C. and Farabella, Irene and Law, R.H.P. and Reboul, C.F. and Caradoc-Davies, T.T. and Spicer, B.A. and Kleifeld, O. and Traore, D.A.K. and Ekkel, S.M. and Voskoboinik, I. and Trapani, J.A. and Hatfaludi, T. and Oliver, K. and Hotze, E.M. and Tweten, R.K. and Whisstock, J.C. and Topf, Maya and Saibil, Helen R. and Dunstone, M.A. (2015) Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLOS Biology 13 (2), e1002049. ISSN 1545-7885.

    Lopez, J.A. and Susanto, O. and Jenkins, M.R. and Lukoyanova, Natalya and Sutton, V.R. and Law, R.H.P. and Johnston, A. and Bird, C.H. and Bird, P I. and Whisstock, J.C. and Trapani, J.A. and Saibil, Helen R. and Voskoboinik, I. (2013) Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 121 (14), pp. 2659-2668. ISSN 0006-4971.

    Law, R.H.P. and Lukoyanova, Natalya and Voskoboinik, I. and Caradoc-Davies, T.T. and Baran, K. and Dunstone, M.A. and d’Angelo, M.E. and Orlova, Elena and Coulibaly, F. and Verschoor, S. and Browne, K.A. and Ciccone, A. and Kuiper, M.J. and Bird, P.I. and Trapani, J.A. and Saibil, Helen R. and Whisstock, J.C. (2010) The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 468 (7322), pp. 447-451. ISSN 0028-0836.

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