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Journal of Medicinal Chemistry

Mallya, M. and Phillips, R.L. and Saldanha, S.A. and Gooptu, Bibek and Leigh Brown, S.C. and Termine, D.J. and Shirvani, A.M. and Wu, Y. and Sifers, R.N. and Abagyan, R. and Lomas, D.A. (2007) Small molecules block the polymerization of Z α1-Antitrypsin and increase the clearance of intracellular aggregates. Journal of Medicinal Chemistry 50 (22), pp. 5357-5363. ISSN 0022-2623.

Gooptu, Bibek and Miranda, E. and Nobeli, Irene and Mallya, M. and Purkiss, Andrew G. and Leigh Brown, S.C. and Summers, C. and Phillips, R.L. and Lomas, D.A. and Barrett, Tracey E. (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of α1-Antitrypsin: implications for disease and drug design. Journal of Molecular Biology 387 (4), pp. 857-868. ISSN 0022-2836.

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