Browse by Person

April 2009

Gooptu, Bibek and Miranda, E. and Nobeli, Irene and Mallya, M. and Purkiss, Andrew G. and Leigh Brown, S.C. and Summers, C. and Phillips, R.L. and Lomas, D.A. and Barrett, Tracey E. (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of α1-Antitrypsin: implications for disease and drug design. Journal of Molecular Biology 387 (4), pp. 857-868. ISSN 0022-2836.

June 2009

Ekeowa, U.I. and Gooptu, Bibek and Belorgey, D. and Hägglöf, P. and Karlsson‑Li, S. and Miranda, E. and Pérez, J. and MacLeod, I. and Kroger, H. and Marciniak, S.J. and Crowther, D.C. and Lomas, D.A. (2009) α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clinical Science 116 (12), pp. 837-850. ISSN 0143-5221.

September 2010

Miranda, E. and Pérez, J. and Ekeowa, U.I. and Hadzic, N. and Kalsheker, N. and Gooptu, Bibek and Portmann, B. and Belorgey, D. and Hill, M. and Chambers, S. and Teckman, J. and Alexander, G.J. and Marciniak, S.J. and Lomas, D.A. (2010) A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency. Hepatology 52 (3), pp. 1078-1088. ISSN 0270-9139.

October 2010

Ekeowa, U.I. and Freeke, J. and Miranda, E. and Gooptu, Bibek and Bush, M.F. and Pérez, J. and Teckman, J. and Robinson, C.V. and Lomas, D.A. (2010) Defining the mechanism of polymerization in the serpinopathies. Proceedings of the National Academy of Sciences of the United States of America 107 (40), pp. 17146-17151. ISSN 0027-8424.

4 December 2011

Irving, J.A. and Ekeowa, U.I. and Belorgey, D. and Haq, I. and Gooptu, Bibek and Miranda, E. and Pérez, J. and Roussel, B.D. and Ordóñez, A. and Dalton, L.E. and Thomas, S.E. and Marciniak, S.J. and Parfrey, H. and Chilvers, E.R. and Teckman, J.H. and Alam, S. and Mahadeva, R. and Rashid, S.T. and Vallier, L. and Lomas, D.A. (2011) The serpinopathies: studying serpin polymerization in vivo. In: Whisstock, J.C. and Bird, P. I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 421-466. ISBN 9780123859501.

5 December 2011

Chang, Y.-P. and Mahadeva, R. and Patschull, A.O.M. and Nobeli, Irene and Ekeowa, U.I. and McKay, A.R. and Thalassinos, Konstantinos and Irving, J.A. and Haq, I. and Nyon, Mun Peak and Christodoulou, John and Ordóñez, A. and Miranda, E. and Gooptu, Bibek (2011) Targeting serpins in high-throughput and structure-based drug design. In: Whisstock, J.C. and Bird, P.I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 139-175. ISBN 9780123859501.

2012

Gasset, M. and Fra, A.M. and Gooptu, Bibek and Ferrarotti, I. and Miranda, E. and Scabini, R. and Ronzoni, R. and Benini, F. and Corda, L. and Medicina, D. and Luisetti, M. and Schiaffonati, L. (2012) Three new Alpha1-Antitrypsin deficiency variants help to define a C-Terminal region regulating conformational change and polymerization. PLoS One 7 (6), ISSN 1932-6203.

January 2015

Tan, L. and Perez, J. and Mela, M. and Miranda, E. and Burling, K.A. and Rouhani, F.N. and DeMeo, D.L. and Haq, I. and Irving, J.A. and Ordóñez, A. and Dickens, J.A. and Brantly, M. and Marciniak, S.J. and Alexander, G.J. and Gooptu, Bibek and Lomas, D.A. (2015) Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody. The International Journal of Biochemistry & Cell Biology 58 , pp. 81-91. ISSN 1357-2725.

December 2015

Moriconi, C. and Ordoñez, A. and Lupo, G. and Gooptu, Bibek and Irving, J.A. and Noto, R. and Martorana, V. and Manno, M. and Timpano, V. and Guadagno, N.A. and Dalton, L. and Marciniak, S.J. and Lomas, D.A. and Miranda, E. (2015) Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum. FEBS Journal 282 (23), pp. 4565-4579. ISSN 1742-464X.