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2009
Loakes, D. and Gallego, J. and Pinheiro, Vitor B. and Kool, Eric T. and Holliger, Philipp (2009) Evolving a polymerase for hydrophobic base analogues. Journal of the American Chemical Society 131 (41), pp. 14827-14837. ISSN 0002-7863.
2010
Attwater, J. and Wochner, A. and Pinheiro, Vitor B. and Coulson, A. and Holliger, P. (2010) Ice as a protocellular medium for RNA replication. Nature Communications 1 (6), pp. 1-8. ISSN 2041-1723.
2012
Pinheiro, Vitor B. and Ong, J.L. and Holliger, P. (2012) Polymerase engineering: from PCR and sequencing to synthetic biology. In: Lutz, S. and Bornscheuer, U.T. (eds.) Protein Engineering Handbook. Weinheim: Wiley-VCH. ISBN 9783527331239.
Pinheiro, Vitor B. and Taylor, A.I. and Cozens, C. and Abramov, M. and Renders, M. and Zhang, S. and Chaput, J.C. and Wengel, J. and Peak-Chew, S.-Y. and McLaughlin, S.H. and Herdewijn, P. and Holliger, P. (2012) Synthetic genetic polymers capable of heredity and evolution. Science 336 (6079), pp. 341-344. ISSN 0036-8075.
Pinheiro, Vitor B. and Loakes, D. and Holliger, P. (2012) Synthetic polymers and their potential as genetic materials. BioEssays 35 (2), pp. 113-122. ISSN 0265-9247.
Pinheiro, Vitor B. and Holliger, P. (2012) The XNA world: progress towards replication and evolution of synthetic genetic polymers. Current Opinion in Chemical Biology 16 (3/4), pp. 245-252. ISSN 1367-5931.
May 2012
Cozens, C. and Pinheiro, Vitor B. and Vaisman, A. and Woodgate, R. and Holliger, P. (2012) A short adaptive path from DNA to RNA polymerases. Proceedings of the National Academy of Sciences of the United States of America 109 (21), pp. 8067-8072. ISSN 0027-8424.
2013
Wynne, S.A. and Pinheiro, Vitor B. and Holliger, P. and Leslie, A.G.W. (2013) Structures of an apo and a binary complex of an evolved archeal b family DNA polymerase capable of synthesising highly cy-dye labelled DNA. PLoS One 8 (8), ISSN 1932-6203.
June 2014
Pinheiro, Vitor B. and Arangundy-Franklin, S. and Holliger, P. (2014) Compartmentalized self-tagging for in vitro-directed evolution of XNA polymerases. Current Protocols In Nucleic Acid Chemistry 57 , 9.9.1-9.9.18.
19 February 2015
Taylor, A.I. and Pinheiro, Vitor B. and Smola, M.J. and Morgunov, A.S. and Peak-Chew, S. and Cozens, C. and Weeks, K.M. and Herdewijn, P. and Holliger, P. (2015) Catalysts from synthetic genetic polymers. Nature 518 (7539), pp. 427-430. ISSN 0028-0836.
23 March 2015
Bande, O. and Abu El Asrar, R. and Braddick, D. and Dumbre, S. and Pezo, V. and Schepers, G. and Pinheiro, Vitor B. and Lescrinier, E. and Holliger, P. and Marlière, P. and Herdewijn, P. (2015) Isoguanine and 5-Methyl-Isocytosine bases, in vitro and in vivo. Chemistry: A European Journal 21 (13), pp. 5009-5022. ISSN 0947-6539.
13 April 2015
Renders, M. and Pinheiro, Vitor B. (2015) Catalysing mirror life. ChemBioChem 16 (6), pp. 899-901. ISSN 1439-4227.
August 2016
Tizei, P.A.G. and Csibra, E. and Torres, L. and Pinheiro, Vitor B. (2016) Selection platforms for directed evolution in synthetic biology. Biochemical Society Transactions 44 (4), pp. 1165-1175. ISSN 0300-5127.
30 November 2016
Torres, L. and Kruger, A. and Csibra, E. and Gianni, E. and Pinheiro, Vitor B. (2016) Synthetic biology approaches to biological containment: pre-emptively tackling potential risks. Essays in Biochemistry 60 (4), pp. 393-410. ISSN 1744-1358.
3 May 2018
Liu, C. and Cozens, C. and Jaziri, F. and Rozenski, J. and Marechal, Amandine and Dumbre, S. and Pezo, V. and Marliere, P. and Pinheiro, Vitor B. and Groaz, E. and Herdewijn, P. (2018) Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers. Journal of the American Chemical Society 140 (21), pp. 6690-6699. ISSN 0002-7863.
4 May 2018
Cozens, C. and Pinheiro, Vitor B. (2018) Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis. Nucleic Acids Research 46 (8), e51. ISSN 0305-1048.
24 May 2018
Heinisch, T. and Schwizer, F. and Garabedian, B. and Csibra, E. and Jeschek, M. and Vallapurackal, J. and Pinheiro, Vitor B. and Marlière, P. and Panke, S. and Ward, T.R. (2018) E. coli surface display of streptavidin for directed evolution of an allylic deallylase. Chemical Science 24 , ISSN 2041-6520.
31 May 2018
Kestemont, D. and Renders, M. and Leonczak, P. and Abramov, M. and Schepers, G. and Pinheiro, Vitor B. and Rozenski, J. and Herdewijn, P. (2018) XNA ligation using T4 DNA ligase in crowding conditions. Chemical Communications 54 , pp. 6408-6411. ISSN 1359-7345.
June 2018
Torres, L.L. and Pinheiro, Vitor B. (2018) Xenobiotic Nucleic Acid (XNA) synthesis by Phi29 DNA Polymerase. Current Protocols in Chemical Biology 10 (2), e41. ISSN 21604762.
30 January 2019
Renders, M. and Dumbre, S. and Abramov, M. and Kestemont, D. and Margamuljana, L. and Largy, E. and Cozens, C. and Vandenameele, J. and Pinheiro, Vitor B. and Toye, D. and Frère, J.-M. and Herdewijn, P. (2019) Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases. Nucleic Acids Research , ISSN 1362-4962.