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Biochemical Journal

Millson, S.H. and Vaughan, Cara K. and Zhai, C. and Ali, M.M.U. and Panaretou, B. and Piper, P.W. and Pearl, L.H. and Prodromou, C. (2008) Chaperone ligand-discrimination by the TPR-domain protein Tah1. Biochemical Journal 413 , pp. 261-268. ISSN 0264-6021.

Development

Hawkins, T.A. and Haramis, A.P. and Etard, C. and Prodromou, C. and Vaughan, Cara K. and Ashworth, R. and Ray, S. and Behra, M. and Holder, N. and Talbot, W.S. and Pearl, L.H. and Strahlem, U. and Wilson, S.W. (2008) The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development 135 , pp. 1147-1156. ISSN 0950-1991.

Drug Discovery Today

Savva, Renos and Prodromou, C. and Driscoll, P.C. (2007) DNA fragmentation based combinatorial approaches to soluble protein expression: part II: library expression, screening and scale-up. Drug Discovery Today 12 (21-22), pp. 939-947. ISSN 1359-6446.

Prodromou, C. and Savva, Renos and Driscoll, P.C. (2007) DNA fragmentation-based combinatorial approaches to soluble protein expression: part I: generating DNA fragment libraries. Drug Discovery Today 12 (21-22), pp. 931-938. ISSN 1359-6446.

FEBS Journal

Vaughan, Cara K. and Piper, P.W. and Pearl, L.H. and Prodromou, C. (2009) A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s. FEBS Journal 276 (1), pp. 199-209. ISSN 1742-464X.

Future Medicinal Chemistry

Maclagan, K. and Tommasi, R. and Laurine, E. and Prodromou, C. and Driscoll, P.C. and Pearl, L.H. and Reich, S. and Savva, Renos (2011) A combinatorial method to enable detailed investigation of protein-protein interactions. Future Medicinal Chemistry 3 (3), pp. 271-282. ISSN 1756-8919.

Journal of Molecular Biology

Nilapwar, S. and Smith, E.P. and Fu, C. and Prodromou, C. and Pearl, L.H. and Williams, Mark A. and Ladbury, J.E. (2009) Structural-thermodynamics relationships of interactions in the N-terminal ATP binding domain of Hsp90. Journal of Molecular Biology 392 (4), pp. 923-936. ISSN 0022-2836.

Nilapwar, S. and Williams, E. and Fu, C. and Prodromou, C. and Pearl, L.H. and Williams, Mark A. and Ladbury, J.E. (2009) Structural–thermodynamic relationships of interactions in the N-Terminal ATP-Binding domain of Hsp90. Journal of Molecular Biology 392 (4), pp. 923-936. ISSN 0022-2836.

Molecular Cell

Mollapour, M. and Tsutsumi, T. and Truman, A.W. and Xu, W. and Vaughan, Cara K. and Beebe, K. and Konstantinova, A. and Vourganti, S. and Panaretou, B. and Piper, P.W. and Trepel, J.B. and Prodromou, C. and Pearl, L.H. and Neckers, L. (2011) Threonine 22 Phosphorylation attenuates Hsp90 interaction with Cochaperones and affects its chaperone activity. Molecular Cell 41 (6), pp. 672-681. ISSN 1097-2765.

Vaughan, Cara K. and Mollapour, M. and Smith, J.R. and Truman, A.W. and Hu, B. and Good, V.M. and Panaretou, B. and Neckers, L. and Clarke, P.A. and Workman, P. and Piper, P.W. and Prodromou, C. and Pearl, L.H. (2008) Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Molecular Cell 31 (6), pp. 886-895. ISSN 1097-2765.

Protein Science

Reich, S. and Puckey, L.H. and Cheetham, C.L. and Harris, R. and Ali, A.A. and Bhattacharyya, U. and Maclagan, K. and Powell, K.A. and Prodromou, C. and Pearl, L.H. and Driscoll, P.C. and Savva, Renos (2006) Combinatorial domain hunting: an effective approach for the identification of soluble protein domains adaptable to high-throughput applications. Protein Science 15 (10), pp. 2356-2365. ISSN 0961-8368.