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Wang, X. and Kirkpatrick, J.P. and Launay, H.M.M and de Simone, A. and Häussinger, D. and Dobson, C.M. and Vendruscolo, M. and Cabrita, L.D. and Waudby, C.A. and Christodoulou, John (2019) Probing the dynamic stalk region of the ribosome using solution NMR. Scientific Reports 9 (1), p. 13528. ISSN 2045-2322.
Waudby, C.A. and Wlodarski, T. and Karyadi, M.-E. and Cassaignau, A.M.E. and Chan, S.H.S. and Wentink, A.S. and Schmidt-Engler, J.M. and Camilloni, C. and Vendruscolo, M. and Cabrita, L.D. and Christodoulou, John (2018) Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 115 (39), pp. 9744-9749. ISSN 0027-8424.
Deckert, Annika and Waudby, Christopher and Wlodarski, Tomasz and Wentink, Anne and Wang, Xiaolin and Kirkpatrick, John and Paton, Jack and Camilloni, C. and Kukic, P. and Dobson, C.M. and Vendruscolo, M. and Cabrita, Lisa and Christodoulou, John (2016) Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor. Proceedings of the National Academy of Sciences of the United States of America 113 (18), pp. 5012-5017. ISSN 0027-8424.
Cabrita, Lisa D. and Cassaignau, Anaïs M.E. and Launay, Hélène M.M. and Waudby, Christopher A. and Wlodarski, Tomasz and Camilloni, C. and Karyadi, Maria-Evangelia and Robertson, Amy L. and Wang, Xiaolin and Wentink, Anne S. and Goodsell, Luke S. and Woolhead, C.A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2016) A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding. Nature Structural & Molecular Biology 23 (4), pp. 278-285. ISSN 1545-9993.
Temussi, P.A. and Waudby, Christopher A. and Camilloni, C. and Fitzpatrick, A.W.P. and Cabrita, L.D. and Dobson, C.M. and Vendruscolo, M. and Christodoulou, John (2013) In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-Synuclein within E. coli cells. PLoS One 8 (8), e72286. ISSN 1932-6203.
O’Brien, E.P. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2012) Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant Cytosolic interactions. Journal of the American Chemical Society 134 (26), pp. 10920-10932. ISSN 0002-7863.
O’Brien, E.P. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2011) New scenarios of protein folding can occur on the Ribosome. Journal of the American Chemical Society 133 (3), pp. 513-526. ISSN 0002-7863.
O’Brien, E.P. and Hsu, S.T.D. and Christodoulou, John and Vendruscolo, M. and Dobson, C.M. (2010) Transient tertiary structure formation within the Ribosome Exit Port. Journal of the American Chemical Society 132 (47), pp. 16928-16937. ISSN 0002-7863.
Lendel, C. and Bertoncini, C.W. and Cremades, N. and Waudby, Christopher A. and Vendruscolo, M. and Dobson, C.M. and Schenk, D. and Christodoulou, John and Toth, G. (2009) On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with congo red and lacmoid. Biochemistry 48 (35), pp. 8322-8334. ISSN 0006-2960.
Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2009) Molecular determinants of the aggregation behavior of α- and β-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.
Rivers, R.C. and Kumita, J.R. and Tartaglia, G.G. and Dedmon, M.M. and Pawar, A. and Vendruscolo, M. and Dobson, C.M. and Christodoulou, John (2008) Molecular determinants of the aggregation behavior of alpha- and beta-synuclein. Protein Science 17 (5), pp. 887-898. ISSN 0961-8368.
Gsponer, J. and Christodoulou, John and Cavalli, A. and Bui, J.M. and Richter, B. and Dobson, C.M. and Vendruscolo, M. (2008) A coupled equilibrium shift mechanism in Calmodulin-Mediated signal transduction. Structure 16 (5), pp. 736-746. ISSN 0969-2126.