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Brennan, A.J. and Law, R.H.P. and Conroy, P.J. and Noori, T. and Lukoyanova, Natalya and Saibil, Helen R. and Yagita, H. and Ciccone, A. and Verschoor, S. and Whisstock, J.C. and Trapani, J.A. and Voskoboinik, I. (2018) Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death & Differentiation 25 , pp. 1517-1529. ISSN 1350-9047.

Leung, C. and Hodel, A.W. and Brennan, A. and Lukoyanova, N. and Tran, S. and House, C.M. and Kondos, S.C. and Whisstock, J.C. and Dunstone, M.A. and Trapani, J.A. and Voskoboinik, I. and Saibil, Helen R. and Hoogenboom, B.W. (2017) Real-time visualization of perforin nanopore assembly. Nature Nanotechnology , ISSN 1748-3387.

Dudkina, Natalya and Spicer, B.A. and Reboul, C.F. and Conroy, P.J. and Lukoyanova, Natalya and Elmlund, H. and Law, R.H.P. and Ekkel, S.M. and Kondos, S.C. and Goode, R.J.A. and Ramm, G. and Whisstock, J.C. and Saibil, Helen R. and Dunstone, M.A. (2016) Structure of the poly-C9 component of the complement membrane attack complex. Nature Communications 7 , p. 10588. ISSN 2041-1723.

Lukoyanova, Natalya and Kondos, S.C. and Farabella, Irene and Law, R.H.P. and Reboul, C.F. and Caradoc-Davies, T.T. and Spicer, B.A. and Kleifeld, O. and Traore, D.A.K. and Ekkel, S.M. and Voskoboinik, I. and Trapani, J.A. and Hatfaludi, T. and Oliver, K. and Hotze, E.M. and Tweten, R.K. and Whisstock, J.C. and Topf, Maya and Saibil, Helen R. and Dunstone, M.A. (2015) Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLoS Biology 13 (2), e1002049. ISSN 1545-7885.

Lopez, J.A. and Susanto, O. and Jenkins, M.R. and Lukoyanova, Natalya and Sutton, V.R. and Law, R.H.P. and Johnston, A. and Bird, C.H. and Bird, P I. and Whisstock, J.C. and Trapani, J.A. and Saibil, Helen R. and Voskoboinik, I. (2013) Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 121 (14), pp. 2659-2668. ISSN 0006-4971.

Traore, DA.K. and Brennan, A.J. and Law, R.H. P. and Dogovski, C. and Perugini, M.A. and Lukoyanova, Natalya and Leung, E.W.W. and Norton, R.S. and Lopez, J.A. and Browne, K.A. and Yagita, H. and Lloyd, G.J. and Ciccone, A. and Verschoor, S. and Trapani, J.A. and Whisstock, J.C. and Voskoboinik, I. (2013) Defining the interaction of perforin with calcium and the phospholipid membrane. Biochemical Journal 456 (3), pp. 323-335. ISSN 0264-6021.

Law, R.H.P. and Lukoyanova, Natalya and Voskoboinik, I. and Caradoc-Davies, T.T. and Baran, K. and Dunstone, M.A. and d’Angelo, M.E. and Orlova, Elena and Coulibaly, F. and Verschoor, S. and Browne, K.A. and Ciccone, A. and Kuiper, M.J. and Bird, P.I. and Trapani, J.A. and Saibil, Helen R. and Whisstock, J.C. (2010) The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 468 (7322), pp. 447-451. ISSN 0028-0836.

Baran, K. and Dunstone, M.A. and Chia, J. and Ciccone, A. and Browne, K.A. and Clarke, C.J.P. and Lukoyanova, Natalya and Saibil, Helen R. and Whisstock, J.C. and Voskoboinik, I. and Trapani, J.A. (2009) The molecular basis for perforin oligomerization and transmembrane pore assembly. Immunity 30 (5), pp. 684-695. ISSN 1074-7613.

Book Section

Chang, Y.-P. and Mahadeva, R. and Patschull, A.O.M. and Nobeli, Irene and Ekeowa, U.I. and McKay, A.R. and Thalassinos, Konstantinos and Irving, J.A. and Haq, I. and Nyon, Mun Peak and Christodoulou, John and Ordóñez, A. and Miranda, E. and Gooptu, Bibek (2011) Targeting serpins in high-throughput and structure-based drug design. In: Whisstock, J.C. and Bird, P.I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 139-175. ISBN 9780123859501.

Irving, J.A. and Ekeowa, U.I. and Belorgey, D. and Haq, I. and Gooptu, Bibek and Miranda, E. and Pérez, J. and Roussel, B.D. and Ordóñez, A. and Dalton, L.E. and Thomas, S.E. and Marciniak, S.J. and Parfrey, H. and Chilvers, E.R. and Teckman, J.H. and Alam, S. and Mahadeva, R. and Rashid, S.T. and Vallier, L. and Lomas, D.A. (2011) The serpinopathies: studying serpin polymerization in vivo. In: Whisstock, J.C. and Bird, P. I. (eds.) Serpin Structure and Evolution. Methods In Enzymology 501. New York, U.S.: Elsevier, pp. 421-466. ISBN 9780123859501.