Orlova, Elena (2015) A molecular syringe that kills cells. Nature Structural & Molecular Biology 22 (5), pp. 357-359. ISSN 1545-9993.
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12080.pdf - Published Version of Record Restricted to Repository staff only Download (1MB) |
Official URL: http://dx.doi.org/10.1038/nsmb.3021
Abstract
R-type pyocins, produced by Pseudomonas aeruginosa, are sheath-tube nanomachines that puncture the envelopes of target cells, inducing their death. Cryo-EM studies reveal the atomic structures of the pyocin R2 in its extended precontraction and postcontraction forms, which suggest a mechanism for the contraction process of this molecular syringe.
Metadata
Item Type: | Article |
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School: | Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences |
Research Centres and Institutes: | Structural Molecular Biology, Institute of (ISMB) |
Depositing User: | Administrator |
Date Deposited: | 07 May 2015 11:43 |
Last Modified: | 02 Aug 2023 17:16 |
URI: | https://eprints.bbk.ac.uk/id/eprint/12080 |
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