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    A molecular syringe that kills cells

    Orlova, Elena (2015) A molecular syringe that kills cells. Nature Structural & Molecular Biology 22 (5), pp. 357-359. ISSN 1545-9993.

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    R-type pyocins, produced by Pseudomonas aeruginosa, are sheath-tube nanomachines that puncture the envelopes of target cells, inducing their death. Cryo-EM studies reveal the atomic structures of the pyocin R2 in its extended precontraction and postcontraction forms, which suggest a mechanism for the contraction process of this molecular syringe.


    Item Type: Article
    School: Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences
    Research Centres and Institutes: Structural Molecular Biology, Institute of (ISMB)
    Depositing User: Administrator
    Date Deposited: 07 May 2015 11:43
    Last Modified: 02 Aug 2023 17:16


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