Aviv, O. and Shemesh, O. and Peres, A. and Polak, P. and Shepherd, Adrian J. and Watson, C.T. and Boyd, S.D. and Collins, A.M. and Lees, William and Yaari, G. (2019) VDJbase: an adaptive immune receptor genotype and haplotype database. Nucleic Acids Research , ISSN 0305-1048.
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Abstract
VDJbase is a publicly available database that offers easy searching of data describing the complete sets of gene sequences (genotypes and haplotypes) inferred from adaptive immune receptor repertoire sequencing datasets. VDJbase is designed to act as a resource that will allow the scientific community to explore the genetic variability of the immunoglobulin (Ig) and T cell receptor (TR) gene loci. It can also assist in the investigation of Ig and TR-related genetic predispositions to diseases. Our database includes web-based query and online tools to assist in visualization and analysis of the genotype and haplotype data. It enables users to detect those alleles and genes that are significantly over-represented in a particular population, in terms of genotype, haplotype and gene expression. The database website can be freely accessed at https://www.vdjbase.org/, and no login is required. The data and code use creative common licenses and are freely downloadable from https://bitbucket. org/account/user/yaarilab/projects/GPHP.
Metadata
| Item Type: | Article |
|---|---|
| School: | Birkbeck Faculties and Schools > Faculty of Science > School of Natural Sciences |
| Research Centres and Institutes: | Data Analytics, Birkbeck Institute for |
| Depositing User: | Adrian Shepherd |
| Date Deposited: | 18 Oct 2019 08:36 |
| Last Modified: | 02 Aug 2023 17:54 |
| URI: | https://eprints.bbk.ac.uk/id/eprint/29465 |
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