Fitzgerald, T. and Brettell, I. and Leger, A. and Wolf, N. and Kusminski, N. and Monahan, J. and Barton, Carl and Herder, C. and Aadepu, N. and Gierten, J. and Becker, C. and Hammouda, O.T. and Hasel, E. and Lischik, C. and Lust, K. and Sokolova, N. and Suzuki, R. and Tsingos, E. and Tavhelidse, T. and Thumberger, T. and Watson, P. and Welz, B. and Khouja, N. and Naruse, K. and Birney, E. and Wittbrodt, J. and Loosli, F. (2022) The Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel. Genome Biology , ISSN 1474-7596.
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Abstract
Unraveling the relationship between genetic variation and phenotypic traits remains a fundamental challenge in biology. Mapping variants underlying complex traits while controlling for confounding environmental factors is often problematic. To address this, we establish a vertebrate genetic resource specifically to allow for robust genotype-to-phenotype investigations. The teleost medaka (Oryzias latipes) is an established genetic model system with a long history of genetic research and a high tolerance to inbreeding from the wild.
Metadata
| Item Type: | Article |
|---|---|
| Keyword(s) / Subject(s): | Inbred panel, Medaka, Genetics, Quantitative traits, Genome sequencing, Population genetics, Copy number variation, eQTL |
| School: | Birkbeck Faculties and Schools > Faculty of Science > School of Computing and Mathematical Sciences |
| Depositing User: | Carl Barton |
| Date Deposited: | 16 May 2022 11:39 |
| Last Modified: | 09 Aug 2023 12:50 |
| URI: | https://eprints.bbk.ac.uk/id/eprint/44356 |
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